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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM41A
All Species:
14.55
Human Site:
S22
Identified Species:
24.62
UniProt:
Q96HV5
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96HV5
NP_542383.1
264
29665
S22
T
F
A
L
Y
L
L
S
T
R
L
P
R
G
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001095986
264
29629
S22
T
F
A
L
Y
L
L
S
T
R
L
P
R
G
R
Dog
Lupus familis
XP_545235
264
29643
S22
T
F
A
L
Y
L
L
S
T
R
L
P
R
G
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9D8U2
264
29351
S22
T
F
A
L
Y
L
L
S
T
R
L
P
L
G
P
Rat
Rattus norvegicus
Q5FVN2
291
32493
G29
D
R
A
V
G
T
Q
G
S
A
A
P
G
N
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513862
323
36410
R16
M
P
R
R
T
S
L
R
F
P
S
D
L
E
E
Chicken
Gallus gallus
Q5ZIL6
269
30250
L16
E
S
A
R
H
Q
R
L
L
E
G
K
A
Q
A
Frog
Xenopus laevis
Q5U4K5
278
31193
N20
T
F
Q
C
N
H
G
N
E
K
K
A
P
A
A
Zebra Danio
Brachydanio rerio
Q502G2
281
31489
E39
H
K
Q
S
H
E
G
E
T
T
D
A
K
D
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VX39
320
35815
P39
Q
V
A
T
P
L
L
P
Q
V
P
P
Q
E
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O62126
246
27484
L16
S
H
P
W
L
V
L
L
I
F
A
T
F
A
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002326733
249
27160
S15
V
G
S
R
F
P
L
S
S
W
E
V
A
A
A
Maize
Zea mays
NP_001141234
254
27619
A21
L
G
A
G
V
A
A
A
F
A
A
G
L
V
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L586
287
32120
N34
S
A
A
K
G
L
L
N
D
D
S
P
T
G
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.8
92.4
N.A.
89
29.8
N.A.
59.7
30.4
30.5
59.7
N.A.
29
N.A.
29.9
N.A.
Protein Similarity:
100
N.A.
99.2
95.8
N.A.
92
52.2
N.A.
65.9
55
53.2
72.5
N.A.
49
N.A.
52.2
N.A.
P-Site Identity:
100
N.A.
100
100
N.A.
86.6
13.3
N.A.
6.6
6.6
13.3
6.6
N.A.
26.6
N.A.
6.6
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
86.6
33.3
N.A.
6.6
13.3
26.6
20
N.A.
40
N.A.
20
N.A.
Percent
Protein Identity:
33.7
32.9
N.A.
33.1
N.A.
N.A.
Protein Similarity:
53.7
51.8
N.A.
52.2
N.A.
N.A.
P-Site Identity:
13.3
6.6
N.A.
33.3
N.A.
N.A.
P-Site Similarity:
33.3
13.3
N.A.
53.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
65
0
0
8
8
8
0
15
22
15
15
22
22
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
0
0
8
8
8
8
0
8
0
% D
% Glu:
8
0
0
0
0
8
0
8
8
8
8
0
0
15
8
% E
% Phe:
0
36
0
0
8
0
0
0
15
8
0
0
8
0
0
% F
% Gly:
0
15
0
8
15
0
15
8
0
0
8
8
8
36
15
% G
% His:
8
8
0
0
15
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% I
% Lys:
0
8
0
8
0
0
0
0
0
8
8
8
8
0
15
% K
% Leu:
8
0
0
29
8
43
65
15
8
0
29
0
22
0
0
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
15
0
0
0
0
0
8
0
% N
% Pro:
0
8
8
0
8
8
0
8
0
8
8
50
8
0
8
% P
% Gln:
8
0
15
0
0
8
8
0
8
0
0
0
8
8
8
% Q
% Arg:
0
8
8
22
0
0
8
8
0
29
0
0
22
0
22
% R
% Ser:
15
8
8
8
0
8
0
36
15
0
15
0
0
0
0
% S
% Thr:
36
0
0
8
8
8
0
0
36
8
0
8
8
0
0
% T
% Val:
8
8
0
8
8
8
0
0
0
8
0
8
0
8
8
% V
% Trp:
0
0
0
8
0
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
0
0
0
0
29
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _