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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM41A
All Species:
13.33
Human Site:
S253
Identified Species:
22.56
UniProt:
Q96HV5
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96HV5
NP_542383.1
264
29665
S253
H
L
Q
L
N
E
T
S
T
A
N
H
I
H
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001095986
264
29629
S253
H
L
Q
L
N
E
T
S
T
A
N
H
I
H
S
Dog
Lupus familis
XP_545235
264
29643
S253
D
L
H
L
N
E
I
S
N
T
N
H
L
N
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9D8U2
264
29351
S253
R
L
A
L
S
E
T
S
D
I
G
H
P
D
R
Rat
Rattus norvegicus
Q5FVN2
291
32493
S265
G
E
A
V
S
W
N
S
V
F
I
L
M
I
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513862
323
36410
V299
T
W
V
G
D
A
S
V
S
G
Y
F
D
P
T
Chicken
Gallus gallus
Q5ZIL6
269
30250
S243
G
E
A
V
S
W
N
S
L
F
V
L
M
I
L
Frog
Xenopus laevis
Q5U4K5
278
31193
S252
G
E
A
V
S
W
N
S
V
I
I
L
M
V
L
Zebra Danio
Brachydanio rerio
Q502G2
281
31489
E270
H
L
H
L
D
G
L
E
T
N
G
L
S
Q
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VX39
320
35815
L309
C
A
S
L
L
P
G
L
L
K
N
K
F
K
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O62126
246
27484
P236
S
A
I
L
S
L
A
P
I
L
L
K
K
K
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002326733
249
27160
I239
F
L
I
G
I
V
S
I
T
P
T
L
I
S
K
Maize
Zea mays
NP_001141234
254
27619
Q243
L
L
G
K
D
E
A
Q
E
K
P
S
E
M
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L586
287
32120
I275
F
L
I
G
S
I
S
I
F
P
A
L
L
K
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.8
92.4
N.A.
89
29.8
N.A.
59.7
30.4
30.5
59.7
N.A.
29
N.A.
29.9
N.A.
Protein Similarity:
100
N.A.
99.2
95.8
N.A.
92
52.2
N.A.
65.9
55
53.2
72.5
N.A.
49
N.A.
52.2
N.A.
P-Site Identity:
100
N.A.
100
53.3
N.A.
40
6.6
N.A.
0
6.6
6.6
26.6
N.A.
13.3
N.A.
6.6
N.A.
P-Site Similarity:
100
N.A.
100
66.6
N.A.
46.6
26.6
N.A.
26.6
26.6
26.6
40
N.A.
13.3
N.A.
13.3
N.A.
Percent
Protein Identity:
33.7
32.9
N.A.
33.1
N.A.
N.A.
Protein Similarity:
53.7
51.8
N.A.
52.2
N.A.
N.A.
P-Site Identity:
20
13.3
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
26.6
26.6
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
29
0
0
8
15
0
0
15
8
0
0
0
8
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
22
0
0
0
8
0
0
0
8
8
0
% D
% Glu:
0
22
0
0
0
36
0
8
8
0
0
0
8
0
0
% E
% Phe:
15
0
0
0
0
0
0
0
8
15
0
8
8
0
0
% F
% Gly:
22
0
8
22
0
8
8
0
0
8
15
0
0
0
0
% G
% His:
22
0
15
0
0
0
0
0
0
0
0
29
0
15
8
% H
% Ile:
0
0
22
0
8
8
8
15
8
15
15
0
22
15
0
% I
% Lys:
0
0
0
8
0
0
0
0
0
15
0
15
8
22
8
% K
% Leu:
8
58
0
50
8
8
8
8
15
8
8
43
15
0
29
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
22
8
0
% M
% Asn:
0
0
0
0
22
0
22
0
8
8
29
0
0
8
8
% N
% Pro:
0
0
0
0
0
8
0
8
0
15
8
0
8
8
0
% P
% Gln:
0
0
15
0
0
0
0
8
0
0
0
0
0
8
0
% Q
% Arg:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
15
% R
% Ser:
8
0
8
0
43
0
22
50
8
0
0
8
8
8
22
% S
% Thr:
8
0
0
0
0
0
22
0
29
8
8
0
0
0
8
% T
% Val:
0
0
8
22
0
8
0
8
15
0
8
0
0
8
0
% V
% Trp:
0
8
0
0
0
22
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _