KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM41A
All Species:
20.91
Human Site:
S46
Identified Species:
35.38
UniProt:
Q96HV5
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96HV5
NP_542383.1
264
29665
S46
G
R
S
L
W
F
P
S
D
L
A
E
L
R
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001095986
264
29629
S46
G
R
S
L
W
F
P
S
D
L
A
E
L
R
E
Dog
Lupus familis
XP_545235
264
29643
S46
G
R
S
L
W
F
P
S
D
L
A
E
L
R
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9D8U2
264
29351
S46
G
R
S
L
W
F
P
S
D
L
A
E
L
R
E
Rat
Rattus norvegicus
Q5FVN2
291
32493
S53
E
A
G
S
A
R
T
S
L
L
I
L
V
S
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513862
323
36410
S40
Y
Y
K
R
E
H
P
S
Y
V
L
L
L
F
C
Chicken
Gallus gallus
Q5ZIL6
269
30250
T40
L
I
L
V
S
I
F
T
I
A
A
F
L
M
F
Frog
Xenopus laevis
Q5U4K5
278
31193
L44
A
R
M
S
L
L
I
L
V
S
I
F
L
C
A
Zebra Danio
Brachydanio rerio
Q502G2
281
31489
S63
S
S
R
L
K
F
P
S
D
L
D
E
L
K
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VX39
320
35815
A63
Q
Q
Q
Q
Q
Q
Q
A
T
P
Q
K
Q
A
M
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O62126
246
27484
K40
P
E
V
S
A
D
E
K
V
H
L
K
Y
P
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002326733
249
27160
T39
G
L
L
G
V
Y
L
T
M
P
E
S
D
Y
S
Maize
Zea mays
NP_001141234
254
27619
R45
Y
S
F
L
K
L
P
R
N
L
Q
E
L
Q
I
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L586
287
32120
F58
S
R
W
E
F
A
V
F
F
T
V
F
L
V
F
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.8
92.4
N.A.
89
29.8
N.A.
59.7
30.4
30.5
59.7
N.A.
29
N.A.
29.9
N.A.
Protein Similarity:
100
N.A.
99.2
95.8
N.A.
92
52.2
N.A.
65.9
55
53.2
72.5
N.A.
49
N.A.
52.2
N.A.
P-Site Identity:
100
N.A.
100
100
N.A.
100
13.3
N.A.
20
13.3
13.3
60
N.A.
0
N.A.
0
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
100
20
N.A.
26.6
26.6
13.3
66.6
N.A.
20
N.A.
6.6
N.A.
Percent
Protein Identity:
33.7
32.9
N.A.
33.1
N.A.
N.A.
Protein Similarity:
53.7
51.8
N.A.
52.2
N.A.
N.A.
P-Site Identity:
6.6
33.3
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
20
46.6
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
15
8
0
8
0
8
36
0
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% C
% Asp:
0
0
0
0
0
8
0
0
36
0
8
0
8
0
0
% D
% Glu:
8
8
0
8
8
0
8
0
0
0
8
43
0
0
36
% E
% Phe:
0
0
8
0
8
36
8
8
8
0
0
22
0
8
15
% F
% Gly:
36
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
8
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
8
8
0
8
0
15
0
0
0
15
% I
% Lys:
0
0
8
0
15
0
0
8
0
0
0
15
0
8
0
% K
% Leu:
8
8
15
43
8
15
8
8
8
50
15
15
72
0
0
% L
% Met:
0
0
8
0
0
0
0
0
8
0
0
0
0
8
8
% M
% Asn:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% N
% Pro:
8
0
0
0
0
0
50
0
0
15
0
0
0
8
0
% P
% Gln:
8
8
8
8
8
8
8
0
0
0
15
0
8
8
0
% Q
% Arg:
0
43
8
8
0
8
0
8
0
0
0
0
0
29
8
% R
% Ser:
15
15
29
22
8
0
0
50
0
8
0
8
0
8
8
% S
% Thr:
0
0
0
0
0
0
8
15
8
8
0
0
0
0
0
% T
% Val:
0
0
8
8
8
0
8
0
15
8
8
0
8
8
0
% V
% Trp:
0
0
8
0
29
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
15
8
0
0
0
8
0
0
8
0
0
0
8
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _