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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM41A
All Species:
6.06
Human Site:
T34
Identified Species:
10.26
UniProt:
Q96HV5
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96HV5
NP_542383.1
264
29665
T34
R
G
R
R
L
G
S
T
E
E
A
G
G
R
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001095986
264
29629
T34
R
G
R
R
L
G
S
T
E
E
A
G
G
R
S
Dog
Lupus familis
XP_545235
264
29643
G34
R
G
R
T
L
G
S
G
E
E
P
G
G
R
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9D8U2
264
29351
A34
L
G
P
R
L
A
A
A
G
E
P
E
G
R
S
Rat
Rattus norvegicus
Q5FVN2
291
32493
E41
G
N
K
D
H
L
K
E
K
P
C
V
E
A
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513862
323
36410
S28
L
E
E
L
R
E
L
S
E
F
L
W
Y
Y
K
Chicken
Gallus gallus
Q5ZIL6
269
30250
A28
A
Q
A
E
G
G
S
A
R
T
S
L
L
I
L
Frog
Xenopus laevis
Q5U4K5
278
31193
S32
P
A
A
G
K
V
H
S
E
G
G
S
A
R
M
Zebra Danio
Brachydanio rerio
Q502G2
281
31489
E51
K
D
G
D
E
P
S
E
M
E
T
A
S
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VX39
320
35815
P51
Q
E
Q
Q
D
L
N
P
Q
Q
Q
Q
Q
Q
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O62126
246
27484
V28
F
A
V
S
I
F
A
V
Y
S
N
F
P
E
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002326733
249
27160
L27
A
A
A
S
S
V
L
L
G
F
V
L
G
L
L
Maize
Zea mays
NP_001141234
254
27619
M33
L
V
G
V
Y
L
S
M
P
D
S
D
Y
S
F
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L586
287
32120
E46
T
G
K
R
T
K
S
E
R
F
P
L
S
R
W
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.8
92.4
N.A.
89
29.8
N.A.
59.7
30.4
30.5
59.7
N.A.
29
N.A.
29.9
N.A.
Protein Similarity:
100
N.A.
99.2
95.8
N.A.
92
52.2
N.A.
65.9
55
53.2
72.5
N.A.
49
N.A.
52.2
N.A.
P-Site Identity:
100
N.A.
100
80
N.A.
46.6
0
N.A.
6.6
13.3
13.3
13.3
N.A.
0
N.A.
0
N.A.
P-Site Similarity:
100
N.A.
100
80
N.A.
53.3
13.3
N.A.
13.3
20
20
20
N.A.
46.6
N.A.
13.3
N.A.
Percent
Protein Identity:
33.7
32.9
N.A.
33.1
N.A.
N.A.
Protein Similarity:
53.7
51.8
N.A.
52.2
N.A.
N.A.
P-Site Identity:
6.6
6.6
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
6.6
20
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
22
22
0
0
8
15
15
0
0
15
8
8
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
0
8
0
15
8
0
0
0
0
8
0
8
0
0
0
% D
% Glu:
0
15
8
8
8
8
0
22
36
36
0
8
8
8
0
% E
% Phe:
8
0
0
0
0
8
0
0
0
22
0
8
0
0
8
% F
% Gly:
8
36
15
8
8
29
0
8
15
8
8
22
36
0
8
% G
% His:
0
0
0
0
8
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
0
0
0
0
0
0
0
8
0
% I
% Lys:
8
0
15
0
8
8
8
0
8
0
0
0
0
0
8
% K
% Leu:
22
0
0
8
29
22
15
8
0
0
8
22
8
8
15
% L
% Met:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
8
% M
% Asn:
0
8
0
0
0
0
8
0
0
0
8
0
0
0
0
% N
% Pro:
8
0
8
0
0
8
0
8
8
8
22
0
8
0
0
% P
% Gln:
8
8
8
8
0
0
0
0
8
8
8
8
8
8
8
% Q
% Arg:
22
0
22
29
8
0
0
0
15
0
0
0
0
43
8
% R
% Ser:
0
0
0
15
8
0
50
15
0
8
15
8
15
15
29
% S
% Thr:
8
0
0
8
8
0
0
15
0
8
8
0
0
0
0
% T
% Val:
0
8
8
8
0
15
0
8
0
0
8
8
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% W
% Tyr:
0
0
0
0
8
0
0
0
8
0
0
0
15
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _