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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM41A
All Species:
17.88
Human Site:
Y79
Identified Species:
30.26
UniProt:
Q96HV5
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96HV5
NP_542383.1
264
29665
Y79
L
F
C
G
A
Y
L
Y
K
Q
G
F
A
I
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001095986
264
29629
Y79
L
F
C
S
A
Y
L
Y
K
Q
G
F
A
I
P
Dog
Lupus familis
XP_545235
264
29643
Y79
L
F
C
S
A
Y
L
Y
K
Q
G
F
A
I
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9D8U2
264
29351
Y79
L
F
C
S
A
Y
L
Y
K
Q
G
F
A
I
P
Rat
Rattus norvegicus
Q5FVN2
291
32493
M86
S
E
E
E
R
V
N
M
K
V
P
R
D
M
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513862
323
36410
G73
I
L
A
G
A
L
F
G
P
W
L
G
L
L
L
Chicken
Gallus gallus
Q5ZIL6
269
30250
A73
I
P
R
D
M
D
D
A
K
A
L
G
K
V
L
Frog
Xenopus laevis
Q5U4K5
278
31193
R77
L
E
K
I
K
V
P
R
D
M
D
D
A
K
A
Zebra Danio
Brachydanio rerio
Q502G2
281
31489
Y96
L
F
C
S
A
Y
L
Y
K
Q
A
F
A
I
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VX39
320
35815
M96
F
V
A
S
L
V
T
M
C
Y
V
Y
A
I
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O62126
246
27484
G73
N
Y
S
V
V
L
C
G
V
I
V
V
Y
V
F
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002326733
249
27160
T72
E
T
Y
T
S
D
Y
T
A
Q
V
L
V
G
Y
Maize
Zea mays
NP_001141234
254
27619
F78
G
Y
C
A
V
Y
I
F
M
Q
T
F
M
I
P
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L586
287
32120
S91
L
K
V
P
R
T
I
S
D
L
R
L
L
K
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.8
92.4
N.A.
89
29.8
N.A.
59.7
30.4
30.5
59.7
N.A.
29
N.A.
29.9
N.A.
Protein Similarity:
100
N.A.
99.2
95.8
N.A.
92
52.2
N.A.
65.9
55
53.2
72.5
N.A.
49
N.A.
52.2
N.A.
P-Site Identity:
100
N.A.
93.3
93.3
N.A.
93.3
6.6
N.A.
13.3
6.6
13.3
86.6
N.A.
13.3
N.A.
0
N.A.
P-Site Similarity:
100
N.A.
93.3
93.3
N.A.
93.3
13.3
N.A.
26.6
20
13.3
86.6
N.A.
20
N.A.
13.3
N.A.
Percent
Protein Identity:
33.7
32.9
N.A.
33.1
N.A.
N.A.
Protein Similarity:
53.7
51.8
N.A.
52.2
N.A.
N.A.
P-Site Identity:
6.6
40
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
13.3
60
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
15
8
43
0
0
8
8
8
8
0
50
0
8
% A
% Cys:
0
0
43
0
0
0
8
0
8
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
15
8
0
15
0
8
8
8
0
8
% D
% Glu:
8
15
8
8
0
0
0
0
0
0
0
0
0
0
8
% E
% Phe:
8
36
0
0
0
0
8
8
0
0
0
43
0
0
15
% F
% Gly:
8
0
0
15
0
0
0
15
0
0
29
15
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
15
0
0
8
0
0
15
0
0
8
0
0
0
50
0
% I
% Lys:
0
8
8
0
8
0
0
0
50
0
0
0
8
15
0
% K
% Leu:
50
8
0
0
8
15
36
0
0
8
15
15
15
8
15
% L
% Met:
0
0
0
0
8
0
0
15
8
8
0
0
8
8
0
% M
% Asn:
8
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% N
% Pro:
0
8
0
8
0
0
8
0
8
0
8
0
0
0
43
% P
% Gln:
0
0
0
0
0
0
0
0
0
50
0
0
0
0
0
% Q
% Arg:
0
0
8
0
15
0
0
8
0
0
8
8
0
0
0
% R
% Ser:
8
0
8
36
8
0
0
8
0
0
0
0
0
0
0
% S
% Thr:
0
8
0
8
0
8
8
8
0
0
8
0
0
0
0
% T
% Val:
0
8
8
8
15
22
0
0
8
8
22
8
8
15
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
0
15
8
0
0
43
8
36
0
8
0
8
8
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _