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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: INTS4 All Species: 31.82
Human Site: S272 Identified Species: 70
UniProt: Q96HW7 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96HW7 NP_291025.3 963 108171 S272 E S I V P I P S S N E E I R L
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001092200 963 108141 S272 E S I V P I P S S N E E I R L
Dog Lupus familis XP_534000 964 108247 S273 E S I V P I P S S N E E I R L
Cat Felis silvestris
Mouse Mus musculus Q8CIM8 964 108174 S273 E S I V P I P S S N E E I R L
Rat Rattus norvegicus XP_218937 964 108237 S273 E S I V P I P S S N E E I R L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_417220 941 105375 S286 E S I V P I P S S N E E I R L
Frog Xenopus laevis Q68F70 969 109237 S274 E S I V P I P S S N E E I R L
Zebra Danio Brachydanio rerio XP_001923719 978 109163 S281 E S I V P I P S S N E E I R L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572488 1022 113404 R329 D Y I L P S D R Q Q E E L R M
Honey Bee Apis mellifera XP_623793 916 101959 D272 E N I I V G S D G E D I R M V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001198975 847 94130 L211 E Q T L D K K L M S G L R K K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.6 97.6 N.A. 96.7 96.6 N.A. N.A. 85.8 83.5 78 N.A. 32 37.6 N.A. 43.3
Protein Similarity: 100 N.A. 99.7 98.4 N.A. 97.9 98 N.A. N.A. 90.9 89.9 87.4 N.A. 50.6 57 N.A. 60
P-Site Identity: 100 N.A. 100 100 N.A. 100 100 N.A. N.A. 100 100 100 N.A. 33.3 13.3 N.A. 6.6
P-Site Similarity: 100 N.A. 100 100 N.A. 100 100 N.A. N.A. 100 100 100 N.A. 60 40 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 0 10 0 10 10 0 0 10 0 0 0 0 % D
% Glu: 91 0 0 0 0 0 0 0 0 10 82 82 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 10 0 0 10 0 10 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 91 10 0 73 0 0 0 0 0 10 73 0 0 % I
% Lys: 0 0 0 0 0 10 10 0 0 0 0 0 0 10 10 % K
% Leu: 0 0 0 19 0 0 0 10 0 0 0 10 10 0 73 % L
% Met: 0 0 0 0 0 0 0 0 10 0 0 0 0 10 10 % M
% Asn: 0 10 0 0 0 0 0 0 0 73 0 0 0 0 0 % N
% Pro: 0 0 0 0 82 0 73 0 0 0 0 0 0 0 0 % P
% Gln: 0 10 0 0 0 0 0 0 10 10 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 10 0 0 0 0 19 82 0 % R
% Ser: 0 73 0 0 0 10 10 73 73 10 0 0 0 0 0 % S
% Thr: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 73 10 0 0 0 0 0 0 0 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _