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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
INTS4
All Species:
33.33
Human Site:
S439
Identified Species:
73.33
UniProt:
Q96HW7
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96HW7
NP_291025.3
963
108171
S439
I
H
T
M
R
K
I
S
N
N
I
T
L
R
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001092200
963
108141
S439
I
H
T
M
R
K
I
S
N
N
I
T
L
R
E
Dog
Lupus familis
XP_534000
964
108247
S440
I
H
T
M
R
K
I
S
N
N
I
T
L
R
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8CIM8
964
108174
S440
I
H
T
M
R
K
I
S
N
N
I
T
L
R
E
Rat
Rattus norvegicus
XP_218937
964
108237
S440
I
H
T
M
R
K
I
S
N
N
I
T
L
R
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417220
941
105375
S453
I
H
T
M
R
K
I
S
N
N
I
T
L
R
E
Frog
Xenopus laevis
Q68F70
969
109237
S441
I
H
T
M
R
K
I
S
D
N
I
T
L
R
E
Zebra Danio
Brachydanio rerio
XP_001923719
978
109163
S448
I
H
V
L
R
Q
I
S
T
H
I
T
L
R
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572488
1022
113404
A496
I
Y
S
L
T
A
I
A
K
H
I
V
L
R
E
Honey Bee
Apis mellifera
XP_623793
916
101959
R429
E
D
F
S
G
E
V
R
E
G
L
H
A
T
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198975
847
94130
T364
L
S
S
I
T
M
V
T
K
S
C
L
H
K
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.6
97.6
N.A.
96.7
96.6
N.A.
N.A.
85.8
83.5
78
N.A.
32
37.6
N.A.
43.3
Protein Similarity:
100
N.A.
99.7
98.4
N.A.
97.9
98
N.A.
N.A.
90.9
89.9
87.4
N.A.
50.6
57
N.A.
60
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
100
93.3
66.6
N.A.
40
0
N.A.
0
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
100
100
86.6
N.A.
73.3
20
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
0
10
0
0
0
0
10
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
0
0
10
0
0
0
0
0
0
% D
% Glu:
10
0
0
0
0
10
0
0
10
0
0
0
0
0
82
% E
% Phe:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
10
0
0
0
0
10
0
0
0
0
0
% G
% His:
0
73
0
0
0
0
0
0
0
19
0
10
10
0
0
% H
% Ile:
82
0
0
10
0
0
82
0
0
0
82
0
0
0
0
% I
% Lys:
0
0
0
0
0
64
0
0
19
0
0
0
0
10
0
% K
% Leu:
10
0
0
19
0
0
0
0
0
0
10
10
82
0
10
% L
% Met:
0
0
0
64
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
55
64
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
73
0
0
10
0
0
0
0
0
82
0
% R
% Ser:
0
10
19
10
0
0
0
73
0
10
0
0
0
0
0
% S
% Thr:
0
0
64
0
19
0
0
10
10
0
0
73
0
10
0
% T
% Val:
0
0
10
0
0
0
19
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _