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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDRGK1
All Species:
46.97
Human Site:
S290
Identified Species:
73.81
UniProt:
Q96HY6
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96HY6
NP_076424.1
314
35611
S290
I
R
Q
R
G
R
V
S
I
A
E
L
A
Q
A
Chimpanzee
Pan troglodytes
XP_001160658
314
35605
S290
I
R
Q
R
G
R
V
S
I
A
E
L
A
Q
A
Rhesus Macaque
Macaca mulatta
XP_001115149
314
35825
S290
I
R
Q
R
G
R
V
S
I
A
E
L
A
Q
A
Dog
Lupus familis
XP_534363
315
35933
S291
I
R
Q
R
G
R
V
S
I
T
E
L
A
Q
A
Cat
Felis silvestris
Mouse
Mus musculus
Q80WW9
315
35959
S291
I
R
Q
R
G
R
V
S
I
T
E
L
A
Q
A
Rat
Rattus norvegicus
NP_001099982
339
38587
S315
I
R
Q
R
G
R
V
S
I
T
E
L
A
Q
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420879
296
34430
S270
I
K
Q
R
G
R
V
S
I
A
E
L
V
Q
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6P0E5
300
34413
G275
A
Q
F
I
K
Q
R
G
R
V
S
I
S
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VDD1
309
34313
S283
I
K
Q
R
G
R
V
S
I
A
E
L
A
E
S
Honey Bee
Apis mellifera
XP_624506
290
33637
S265
V
R
Q
R
G
R
I
S
I
T
E
L
A
E
N
Nematode Worm
Caenorhab. elegans
P34623
302
35053
R279
K
F
I
N
Q
R
G
R
V
S
I
H
E
I
A
Sea Urchin
Strong. purpuratus
XP_798584
191
22251
S168
I
A
E
L
A
E
A
S
N
Q
L
V
S
L
N
Poplar Tree
Populus trichocarpa
XP_002319285
298
34199
S265
I
K
R
Q
G
R
V
S
I
S
H
L
A
S
K
Maize
Zea mays
NP_001140487
307
34762
S271
I
R
K
Q
G
R
V
S
I
S
H
L
A
N
N
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94C53
298
34000
S263
I
K
R
Q
G
R
V
S
I
S
H
L
A
S
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
95.8
89.8
N.A.
84.4
79.6
N.A.
N.A.
64.9
N.A.
56
N.A.
41.7
45.2
36.9
41
Protein Similarity:
100
99.3
96.1
93.3
N.A.
89.8
83.7
N.A.
N.A.
78
N.A.
71.9
N.A.
60.5
59.8
57
49.6
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
86.6
N.A.
0
N.A.
80
66.6
13.3
13.3
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
93.3
N.A.
33.3
N.A.
100
86.6
26.6
33.3
Percent
Protein Identity:
34
36.3
N.A.
36.9
N.A.
N.A.
Protein Similarity:
53.8
52.8
N.A.
55.7
N.A.
N.A.
P-Site Identity:
53.3
60
N.A.
53.3
N.A.
N.A.
P-Site Similarity:
80
80
N.A.
80
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
0
7
0
7
0
0
34
0
0
74
0
54
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
7
0
0
7
0
0
0
0
60
0
7
20
0
% E
% Phe:
0
7
7
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
80
0
7
7
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
20
7
0
0
0
% H
% Ile:
80
0
7
7
0
0
7
0
80
0
7
7
0
7
0
% I
% Lys:
7
27
7
0
7
0
0
0
0
0
0
0
0
0
14
% K
% Leu:
0
0
0
7
0
0
0
0
0
0
7
80
0
7
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
7
0
0
0
0
7
0
0
0
0
7
20
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
7
60
20
7
7
0
0
0
7
0
0
0
47
0
% Q
% Arg:
0
54
14
60
0
87
7
7
7
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
87
0
27
7
0
14
14
7
% S
% Thr:
0
0
0
0
0
0
0
0
0
27
0
0
0
0
0
% T
% Val:
7
0
0
0
0
0
74
0
7
7
0
7
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _