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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDRGK1
All Species:
50.91
Human Site:
Y270
Identified Species:
80
UniProt:
Q96HY6
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96HY6
NP_076424.1
314
35611
Y270
D
D
R
G
K
F
I
Y
I
T
P
E
E
L
A
Chimpanzee
Pan troglodytes
XP_001160658
314
35605
Y270
D
D
R
G
K
F
I
Y
I
T
P
E
E
L
A
Rhesus Macaque
Macaca mulatta
XP_001115149
314
35825
Y270
D
D
R
G
K
F
I
Y
I
T
P
E
E
L
A
Dog
Lupus familis
XP_534363
315
35933
Y271
D
D
R
G
K
F
I
Y
I
T
P
E
E
L
A
Cat
Felis silvestris
Mouse
Mus musculus
Q80WW9
315
35959
Y271
D
D
R
G
K
F
I
Y
I
T
P
E
E
L
A
Rat
Rattus norvegicus
NP_001099982
339
38587
Y295
D
D
R
G
K
F
I
Y
I
T
P
E
E
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420879
296
34430
Y250
D
D
R
G
K
F
I
Y
I
T
P
E
E
M
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6P0E5
300
34413
F258
D
D
R
G
K
F
I
F
I
T
P
E
E
L
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VDD1
309
34313
Y263
D
D
R
G
K
F
I
Y
V
S
E
K
E
L
L
Honey Bee
Apis mellifera
XP_624506
290
33637
Y245
D
D
R
G
K
F
I
Y
I
S
Q
E
E
L
E
Nematode Worm
Caenorhab. elegans
P34623
302
35053
Y261
D
D
R
G
K
F
I
Y
I
S
D
E
E
F
A
Sea Urchin
Strong. purpuratus
XP_798584
191
22251
K151
E
E
L
E
A
V
A
K
F
I
R
Q
R
G
R
Poplar Tree
Populus trichocarpa
XP_002319285
298
34199
Y245
D
D
R
G
K
Y
I
Y
I
S
Q
E
E
M
R
Maize
Zea mays
NP_001140487
307
34762
Y251
D
D
R
G
K
F
I
Y
I
S
T
E
E
M
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94C53
298
34000
Y243
D
D
R
G
K
Y
I
Y
I
S
M
E
E
M
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
95.8
89.8
N.A.
84.4
79.6
N.A.
N.A.
64.9
N.A.
56
N.A.
41.7
45.2
36.9
41
Protein Similarity:
100
99.3
96.1
93.3
N.A.
89.8
83.7
N.A.
N.A.
78
N.A.
71.9
N.A.
60.5
59.8
57
49.6
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
93.3
N.A.
86.6
N.A.
66.6
80
80
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
N.A.
93.3
N.A.
86.6
86.6
86.6
20
Percent
Protein Identity:
34
36.3
N.A.
36.9
N.A.
N.A.
Protein Similarity:
53.8
52.8
N.A.
55.7
N.A.
N.A.
P-Site Identity:
66.6
73.3
N.A.
66.6
N.A.
N.A.
P-Site Similarity:
86.6
86.6
N.A.
86.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
0
7
0
0
0
0
0
0
0
54
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
94
94
0
0
0
0
0
0
0
0
7
0
0
0
0
% D
% Glu:
7
7
0
7
0
0
0
0
0
0
7
87
94
0
7
% E
% Phe:
0
0
0
0
0
80
0
7
7
0
0
0
0
7
0
% F
% Gly:
0
0
0
94
0
0
0
0
0
0
0
0
0
7
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
94
0
87
7
0
0
0
0
0
% I
% Lys:
0
0
0
0
94
0
0
7
0
0
0
7
0
0
7
% K
% Leu:
0
0
7
0
0
0
0
0
0
0
0
0
0
60
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
7
0
0
27
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
14
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
54
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
14
7
0
0
0
% Q
% Arg:
0
0
94
0
0
0
0
0
0
0
7
0
7
0
14
% R
% Ser:
0
0
0
0
0
0
0
0
0
40
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
54
7
0
0
0
0
% T
% Val:
0
0
0
0
0
7
0
0
7
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
14
0
87
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _