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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHTKD1
All Species:
35.45
Human Site:
S173
Identified Species:
65
UniProt:
Q96HY7
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96HY7
NP_061176.3
919
103043
S173
L
S
K
L
M
L
E
S
Q
E
F
D
H
F
L
Chimpanzee
Pan troglodytes
XP_001135864
919
102885
S173
L
S
K
L
M
L
E
S
Q
E
F
D
H
F
L
Rhesus Macaque
Macaca mulatta
XP_001085071
1486
164008
E226
T
A
G
L
L
N
M
E
K
E
E
A
S
L
E
Dog
Lupus familis
XP_535192
1115
124145
S369
L
S
K
L
M
L
E
S
Q
E
F
D
H
F
L
Cat
Felis silvestris
Mouse
Mus musculus
A2ATU0
921
102775
S174
L
S
K
L
L
L
E
S
Q
E
F
D
H
F
L
Rat
Rattus norvegicus
Q4KLP0
920
102623
S173
L
S
K
L
L
L
E
S
Q
E
F
D
H
F
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515774
1004
111727
S259
L
S
K
L
M
L
E
S
Q
E
F
D
H
F
L
Chicken
Gallus gallus
XP_423753
1189
132343
S334
L
C
K
L
M
L
E
S
Q
E
F
D
R
F
L
Frog
Xenopus laevis
Q6P286
927
104085
C181
L
A
R
L
M
L
E
C
Q
E
F
D
H
F
L
Zebra Danio
Brachydanio rerio
Q5PRA2
920
102946
S174
L
A
K
L
M
L
E
S
Q
E
F
D
H
F
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VA02
919
103617
S175
I
A
E
L
L
I
K
S
Q
A
W
D
N
F
M
Honey Bee
Apis mellifera
XP_396024
859
97449
A158
E
G
A
E
S
M
L
A
F
Y
H
E
F
F
K
Nematode Worm
Caenorhab. elegans
Q23629
911
102713
C163
I
G
D
L
M
L
K
C
E
N
F
D
K
F
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
36.7
75.4
N.A.
87.8
88.3
N.A.
77.9
62.9
76.4
70.9
N.A.
48.2
49.7
49.9
N.A.
Protein Similarity:
100
99.2
45.2
79
N.A.
93.2
92.9
N.A.
84.3
69.6
86.7
82.8
N.A.
67.9
66.6
66.2
N.A.
P-Site Identity:
100
100
13.3
100
N.A.
93.3
93.3
N.A.
100
86.6
80
93.3
N.A.
33.3
6.6
46.6
N.A.
P-Site Similarity:
100
100
33.3
100
N.A.
100
100
N.A.
100
86.6
93.3
100
N.A.
93.3
26.6
66.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
31
8
0
0
0
0
8
0
8
0
8
0
0
0
% A
% Cys:
0
8
0
0
0
0
0
16
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
0
0
0
0
0
85
0
0
0
% D
% Glu:
8
0
8
8
0
0
70
8
8
77
8
8
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
77
0
8
93
0
% F
% Gly:
0
16
8
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
0
62
0
0
% H
% Ile:
16
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
62
0
0
0
16
0
8
0
0
0
8
0
8
% K
% Leu:
70
0
0
93
31
77
8
0
0
0
0
0
0
8
77
% L
% Met:
0
0
0
0
62
8
8
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
0
8
0
0
0
8
0
0
8
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
77
0
0
0
0
0
0
% Q
% Arg:
0
0
8
0
0
0
0
0
0
0
0
0
8
0
0
% R
% Ser:
0
47
0
0
8
0
0
70
0
0
0
0
8
0
0
% S
% Thr:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _