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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HES6
All Species:
10.91
Human Site:
S140
Identified Species:
24
UniProt:
Q96HZ4
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96HZ4
NP_001136325.1
224
24129
S140
M
P
L
R
E
G
S
S
F
Q
D
L
L
G
D
Chimpanzee
Pan troglodytes
XP_001162539
274
28840
T148
M
T
Q
I
N
A
M
T
Y
P
G
Q
P
H
P
Rhesus Macaque
Macaca mulatta
XP_001095056
150
16253
R72
E
V
L
E
L
T
V
R
R
V
Q
G
V
L
R
Dog
Lupus familis
XP_849016
234
24827
S150
M
P
L
R
E
G
S
S
F
R
D
L
L
G
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9JHE6
224
24436
S140
M
P
L
R
E
G
S
S
F
Q
D
L
L
G
D
Rat
Rattus norvegicus
Q04666
281
29603
T154
M
T
Q
I
N
A
M
T
Y
P
G
Q
A
H
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506283
261
28732
F178
M
P
L
N
E
G
S
F
Q
D
L
L
V
D
A
Chicken
Gallus gallus
O57337
290
31053
N155
L
G
Q
I
V
A
M
N
Y
L
P
P
P
P
A
Frog
Xenopus laevis
Q90VV1
277
29807
N154
L
G
Q
I
V
A
M
N
Y
Q
Q
P
P
S
S
Zebra Danio
Brachydanio rerio
Q8AXV6
317
33920
A166
S
Y
A
S
Q
R
E
A
H
S
G
L
G
H
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q26263
435
46532
G160
A
N
S
L
E
Q
I
G
S
M
S
N
F
S
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
29.2
64.2
69.2
N.A.
85.7
29.1
N.A.
52.8
31
29.9
25.2
N.A.
22.9
N.A.
N.A.
N.A.
Protein Similarity:
100
44.8
64.7
76.5
N.A.
90.1
44.4
N.A.
63.2
45.8
45.8
39.7
N.A.
32.6
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
6.6
93.3
N.A.
100
6.6
N.A.
46.6
0
6.6
6.6
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
13.3
100
N.A.
100
20
N.A.
53.3
20
26.6
20
N.A.
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
0
0
37
0
10
0
0
0
0
10
0
19
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
10
28
0
0
10
28
% D
% Glu:
10
0
0
10
46
0
10
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
10
28
0
0
0
10
0
0
% F
% Gly:
0
19
0
0
0
37
0
10
0
0
28
10
10
28
0
% G
% His:
0
0
0
0
0
0
0
0
10
0
0
0
0
28
0
% H
% Ile:
0
0
0
37
0
0
10
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
19
0
46
10
10
0
0
0
0
10
10
46
28
10
10
% L
% Met:
55
0
0
0
0
0
37
0
0
10
0
0
0
0
0
% M
% Asn:
0
10
0
10
19
0
0
19
0
0
0
10
0
0
10
% N
% Pro:
0
37
0
0
0
0
0
0
0
19
10
19
28
10
19
% P
% Gln:
0
0
37
0
10
10
0
0
10
28
19
19
0
0
0
% Q
% Arg:
0
0
0
28
0
10
0
10
10
10
0
0
0
0
10
% R
% Ser:
10
0
10
10
0
0
37
28
10
10
10
0
0
19
10
% S
% Thr:
0
19
0
0
0
10
0
19
0
0
0
0
0
0
0
% T
% Val:
0
10
0
0
19
0
10
0
0
10
0
0
19
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
0
37
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _