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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABHD8 All Species: 5.76
Human Site: S423 Identified Species: 15.83
UniProt: Q96I13 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96I13 NP_078803.4 439 47331 S423 L L W E P E P S P K A L P E P
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_541956 441 47801 S425 L L W E P E P S P K A L P E P
Cat Felis silvestris
Mouse Mus musculus Q8R0P8 439 48210 E415 L L W E P E P E A E P K L E P
Rat Rattus norvegicus NP_001100771 441 48349 E415 L L W E P E P E A E P K L E P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519519 436 47107 V426 L L W E P D A V G P P A A L E
Chicken Gallus gallus
Frog Xenopus laevis Q6AX59 424 47257 Q414 F L W Q P E T Q N T T A E D T
Zebra Danio Brachydanio rerio XP_691383 482 53252 A417 F L W Q P A T A S K P K Q E A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783117 479 52978 S441 I L K D M T I S L A M Q R G H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SQU2 199 21138 W192 L L L V L S I W S A L S K R T
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 95.2 N.A. 88.6 87.3 N.A. 80.6 N.A. 69.6 59.5 N.A. N.A. N.A. N.A. 31.9
Protein Similarity: 100 N.A. N.A. 95.9 N.A. 91.5 90.4 N.A. 84.7 N.A. 80.1 70.5 N.A. N.A. N.A. N.A. 46.9
P-Site Identity: 100 N.A. N.A. 100 N.A. 60 60 N.A. 33.3 N.A. 26.6 33.3 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 N.A. N.A. 100 N.A. 66.6 66.6 N.A. 40 N.A. 40 46.6 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. 20.2 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 30.5 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 12 12 12 23 23 23 23 12 0 12 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 12 0 12 0 0 0 0 0 0 0 12 0 % D
% Glu: 0 0 0 56 0 56 0 23 0 23 0 0 12 56 12 % E
% Phe: 23 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 12 0 0 0 0 12 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12 % H
% Ile: 12 0 0 0 0 0 23 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 12 0 0 0 0 0 0 34 0 34 12 0 0 % K
% Leu: 67 100 12 0 12 0 0 0 12 0 12 23 23 12 0 % L
% Met: 0 0 0 0 12 0 0 0 0 0 12 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 12 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 78 0 45 0 23 12 45 0 23 0 45 % P
% Gln: 0 0 0 23 0 0 0 12 0 0 0 12 12 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 12 12 0 % R
% Ser: 0 0 0 0 0 12 0 34 23 0 0 12 0 0 0 % S
% Thr: 0 0 0 0 0 12 23 0 0 12 12 0 0 0 23 % T
% Val: 0 0 0 12 0 0 0 12 0 0 0 0 0 0 0 % V
% Trp: 0 0 78 0 0 0 0 12 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _