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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SCLY
All Species:
11.82
Human Site:
S142
Identified Species:
20
UniProt:
Q96I15
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96I15
NP_057594.3
445
48149
S142
K
P
H
F
I
T
S
S
V
E
H
D
S
I
R
Chimpanzee
Pan troglodytes
XP_516185
456
49030
S142
K
P
H
F
I
T
S
S
V
E
H
D
S
I
R
Rhesus Macaque
Macaca mulatta
XP_001085800
445
48195
L142
K
P
H
F
I
T
S
L
V
E
H
D
S
I
R
Dog
Lupus familis
XP_534618
444
48534
T141
V
P
H
L
I
T
C
T
V
E
H
D
S
I
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLI6
432
47155
D134
I
T
C
T
V
E
H
D
S
I
R
L
P
L
E
Rat
Rattus norvegicus
Q68FT9
432
47237
D134
I
T
C
T
V
E
H
D
S
I
R
L
P
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513711
443
48507
S137
P
K
P
H
F
I
T
S
S
V
E
H
D
S
I
Chicken
Gallus gallus
NP_001132935
423
45535
G134
P
L
E
Q
L
V
K
G
H
L
A
E
T
T
F
Frog
Xenopus laevis
Q66IQ6
426
46244
T138
P
L
L
Q
L
Q
K
T
H
K
A
E
I
T
F
Zebra Danio
Brachydanio rerio
NP_001103853
450
49170
S147
S
L
P
H
V
I
I
S
N
V
E
H
D
S
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_495258
328
35781
Y66
D
G
E
I
S
V
T
Y
V
S
I
N
P
L
T
Sea Urchin
Strong. purpuratus
XP_788466
454
49588
K154
N
L
E
H
N
S
I
K
L
P
L
E
H
L
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O49543
453
50277
D140
G
V
M
H
F
Y
K
D
T
K
K
H
V
I
T
Baker's Yeast
Sacchar. cerevisiae
P25374
497
54449
K153
N
A
R
A
H
V
A
K
M
I
N
A
D
P
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.8
95.9
80.4
N.A.
78.4
77.9
N.A.
72.8
66.5
59.7
58.6
N.A.
N.A.
N.A.
32.8
54.8
Protein Similarity:
100
83.3
97.9
88.3
N.A.
88
87.4
N.A.
83.3
79
76.1
74.6
N.A.
N.A.
N.A.
46.9
70.2
P-Site Identity:
100
100
93.3
73.3
N.A.
0
0
N.A.
6.6
0
0
6.6
N.A.
N.A.
N.A.
6.6
0
P-Site Similarity:
100
100
93.3
80
N.A.
13.3
13.3
N.A.
13.3
20
26.6
13.3
N.A.
N.A.
N.A.
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.5
20.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
42.8
39.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
8
0
0
8
0
0
0
15
8
0
0
0
% A
% Cys:
0
0
15
0
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
0
22
0
0
0
29
22
0
0
% D
% Glu:
0
0
22
0
0
15
0
0
0
29
15
22
0
0
15
% E
% Phe:
0
0
0
22
15
0
0
0
0
0
0
0
0
0
15
% F
% Gly:
8
8
0
0
0
0
0
8
0
0
0
0
0
0
0
% G
% His:
0
0
29
29
8
0
15
0
15
0
29
22
8
0
0
% H
% Ile:
15
0
0
8
29
15
15
0
0
22
8
0
8
36
15
% I
% Lys:
22
8
0
0
0
0
22
15
0
15
8
0
0
0
8
% K
% Leu:
0
29
8
8
15
0
0
8
8
8
8
15
0
29
0
% L
% Met:
0
0
8
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
15
0
0
0
8
0
0
0
8
0
8
8
0
0
0
% N
% Pro:
22
29
15
0
0
0
0
0
0
8
0
0
22
8
0
% P
% Gln:
0
0
0
15
0
8
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
8
0
0
0
0
0
0
0
15
0
0
0
29
% R
% Ser:
8
0
0
0
8
8
22
29
22
8
0
0
29
15
0
% S
% Thr:
0
15
0
15
0
29
15
15
8
0
0
0
8
15
15
% T
% Val:
8
8
0
0
22
22
0
0
36
15
0
0
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _