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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SCLY
All Species:
47.58
Human Site:
T422
Identified Species:
80.51
UniProt:
Q96I15
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96I15
NP_057594.3
445
48149
T422
R
L
S
V
G
R
S
T
T
R
A
E
V
D
L
Chimpanzee
Pan troglodytes
XP_516185
456
49030
T433
R
L
S
V
G
R
S
T
T
R
A
E
V
D
L
Rhesus Macaque
Macaca mulatta
XP_001085800
445
48195
T422
R
L
S
V
G
R
S
T
T
R
A
E
V
D
L
Dog
Lupus familis
XP_534618
444
48534
T421
R
L
S
V
G
R
S
T
T
R
A
D
V
D
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLI6
432
47155
T409
R
L
S
V
G
R
G
T
T
R
A
D
V
D
L
Rat
Rattus norvegicus
Q68FT9
432
47237
T409
R
L
S
V
G
R
S
T
T
R
A
E
V
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513711
443
48507
T418
R
L
S
V
G
R
N
T
T
E
E
D
V
D
C
Chicken
Gallus gallus
NP_001132935
423
45535
T398
R
L
S
V
G
R
D
T
T
R
A
D
V
D
L
Frog
Xenopus laevis
Q66IQ6
426
46244
T401
R
L
S
V
G
R
E
T
S
Q
D
D
V
D
L
Zebra Danio
Brachydanio rerio
NP_001103853
450
49170
T427
R
I
S
V
G
R
S
T
S
R
E
D
V
D
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_495258
328
35781
E320
E
I
E
T
V
V
D
E
L
V
Q
L
C
S
P
Sea Urchin
Strong. purpuratus
XP_788466
454
49588
T429
R
L
S
V
G
R
H
T
T
L
E
D
I
D
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O49543
453
50277
T410
R
F
G
I
G
R
F
T
T
K
E
E
I
D
K
Baker's Yeast
Sacchar. cerevisiae
P25374
497
54449
S454
R
F
G
I
G
R
F
S
T
E
E
E
V
D
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.8
95.9
80.4
N.A.
78.4
77.9
N.A.
72.8
66.5
59.7
58.6
N.A.
N.A.
N.A.
32.8
54.8
Protein Similarity:
100
83.3
97.9
88.3
N.A.
88
87.4
N.A.
83.3
79
76.1
74.6
N.A.
N.A.
N.A.
46.9
70.2
P-Site Identity:
100
100
100
86.6
N.A.
86.6
100
N.A.
66.6
86.6
66.6
73.3
N.A.
N.A.
N.A.
0
60
P-Site Similarity:
100
100
100
100
N.A.
93.3
100
N.A.
80
93.3
86.6
93.3
N.A.
N.A.
N.A.
6.6
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.5
20.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
42.8
39.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
46.6
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
50
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% C
% Asp:
0
0
0
0
0
0
15
0
0
0
8
50
0
93
0
% D
% Glu:
8
0
8
0
0
0
8
8
0
15
36
43
0
0
0
% E
% Phe:
0
15
0
0
0
0
15
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
15
0
93
0
8
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
15
0
15
0
0
0
0
0
0
0
0
15
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
8
% K
% Leu:
0
72
0
0
0
0
0
0
8
8
0
8
0
0
58
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
8
0
0
0
0
% Q
% Arg:
93
0
0
0
0
93
0
0
0
58
0
0
0
0
0
% R
% Ser:
0
0
79
0
0
0
43
8
15
0
0
0
0
8
0
% S
% Thr:
0
0
0
8
0
0
0
86
79
0
0
0
0
0
0
% T
% Val:
0
0
0
79
8
8
0
0
0
8
0
0
79
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _