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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SCLY All Species: 37.58
Human Site: Y329 Identified Species: 63.59
UniProt: Q96I15 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96I15 NP_057594.3 445 48149 Y329 H M R D V R D Y L E E R L E A
Chimpanzee Pan troglodytes XP_516185 456 49030 L329 D S N Q A Q V L L C E G R D C
Rhesus Macaque Macaca mulatta XP_001085800 445 48195 Y329 H M R D I R D Y L E E R L E A
Dog Lupus familis XP_534618 444 48534 Y328 H M R D V R D Y L E E R L E A
Cat Felis silvestris
Mouse Mus musculus Q9JLI6 432 47155 Y317 H M R D I R D Y L E E R L E A
Rat Rattus norvegicus Q68FT9 432 47237 Y317 H M R D I R D Y L E E R L E A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513711 443 48507 Y325 H M R K V R D Y L E G R L E A
Chicken Gallus gallus NP_001132935 423 45535 Y305 H M Q D V R D Y L E A R L E A
Frog Xenopus laevis Q66IQ6 426 46244 Y309 H M R R I R D Y L E Q K L E A
Zebra Danio Brachydanio rerio NP_001103853 450 49170 Y334 H F L E I R C Y L E Q K L L A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_495258 328 35781 I236 K R L R N S H I I H F I G S Q
Sea Urchin Strong. purpuratus XP_788466 454 49588 Y337 K M R K V R D Y L E E S L K S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O49543 453 50277 R324 W I K G L Q E R L L N G V R E
Baker's Yeast Sacchar. cerevisiae P25374 497 54449 K369 H I K R L S D K L V K G L L S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 79.8 95.9 80.4 N.A. 78.4 77.9 N.A. 72.8 66.5 59.7 58.6 N.A. N.A. N.A. 32.8 54.8
Protein Similarity: 100 83.3 97.9 88.3 N.A. 88 87.4 N.A. 83.3 79 76.1 74.6 N.A. N.A. N.A. 46.9 70.2
P-Site Identity: 100 13.3 93.3 100 N.A. 93.3 93.3 N.A. 86.6 86.6 73.3 46.6 N.A. N.A. N.A. 0 66.6
P-Site Similarity: 100 26.6 100 100 N.A. 100 100 N.A. 86.6 93.3 93.3 73.3 N.A. N.A. N.A. 6.6 80
Percent
Protein Identity: N.A. N.A. N.A. 24.5 20.9 N.A.
Protein Similarity: N.A. N.A. N.A. 42.8 39.6 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 26.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 46.6 60 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 8 0 0 0 0 0 8 0 0 0 65 % A
% Cys: 0 0 0 0 0 0 8 0 0 8 0 0 0 0 8 % C
% Asp: 8 0 0 43 0 0 72 0 0 0 0 0 0 8 0 % D
% Glu: 0 0 0 8 0 0 8 0 0 72 50 0 0 58 8 % E
% Phe: 0 8 0 0 0 0 0 0 0 0 8 0 0 0 0 % F
% Gly: 0 0 0 8 0 0 0 0 0 0 8 22 8 0 0 % G
% His: 72 0 0 0 0 0 8 0 0 8 0 0 0 0 0 % H
% Ile: 0 15 0 0 36 0 0 8 8 0 0 8 0 0 0 % I
% Lys: 15 0 15 15 0 0 0 8 0 0 8 15 0 8 0 % K
% Leu: 0 0 15 0 15 0 0 8 93 8 0 0 79 15 0 % L
% Met: 0 65 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 0 8 0 0 0 0 0 8 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 8 8 0 15 0 0 0 0 15 0 0 0 8 % Q
% Arg: 0 8 58 22 0 72 0 8 0 0 0 50 8 8 0 % R
% Ser: 0 8 0 0 0 15 0 0 0 0 0 8 0 8 15 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 36 0 8 0 0 8 0 0 8 0 0 % V
% Trp: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 72 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _