KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP1R16A
All Species:
20
Human Site:
S199
Identified Species:
36.67
UniProt:
Q96I34
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96I34
NP_116291.1
528
57811
S199
D
R
G
I
T
Q
D
S
I
E
A
A
R
A
V
Chimpanzee
Pan troglodytes
XP_528270
444
49041
T146
T
P
L
H
A
A
A
T
C
G
H
L
H
L
V
Rhesus Macaque
Macaca mulatta
XP_001093496
528
57587
S199
D
R
G
I
T
Q
D
S
I
E
A
A
R
A
V
Dog
Lupus familis
XP_539220
524
57478
S199
N
R
G
I
T
Q
D
S
I
E
G
A
R
A
L
Cat
Felis silvestris
Mouse
Mus musculus
Q923M0
524
57511
G199
N
Q
G
I
T
Q
E
G
I
E
E
A
R
A
V
Rat
Rattus norvegicus
NP_001124038
525
57775
S200
N
R
G
I
T
Q
D
S
I
E
E
A
R
A
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518754
485
52245
S199
D
Q
G
I
T
Q
D
S
I
E
E
A
R
S
A
Chicken
Gallus gallus
NP_001026022
571
63240
K195
Y
Q
G
I
T
Q
E
K
I
N
E
M
R
A
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001334473
553
60118
K195
E
Q
G
I
T
Q
E
K
I
D
E
C
R
G
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649049
741
80592
L247
Q
R
G
V
T
Q
E
L
I
D
E
T
R
S
S
Honey Bee
Apis mellifera
XP_395019
523
58785
L189
R
R
G
V
T
Q
E
L
I
D
E
T
R
A
S
Nematode Worm
Caenorhab. elegans
NP_492587
480
54271
Y185
A
R
G
I
T
Q
S
Y
I
D
E
M
R
G
A
Sea Urchin
Strong. purpuratus
XP_800118
682
76126
Q196
T
Q
G
I
T
Q
E
Q
I
D
E
L
R
E
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.5
96.5
84
N.A.
82.3
82.9
N.A.
66.6
46.9
N.A.
55.3
N.A.
33
40.1
34.4
33.2
Protein Similarity:
100
83.9
97.3
88.6
N.A.
88
88.6
N.A.
74.6
60.9
N.A.
68.9
N.A.
45.2
58.3
52
49.4
P-Site Identity:
100
6.6
100
80
N.A.
66.6
86.6
N.A.
73.3
46.6
N.A.
40
N.A.
40
46.6
46.6
40
P-Site Similarity:
100
13.3
100
93.3
N.A.
86.6
93.3
N.A.
86.6
60
N.A.
66.6
N.A.
66.6
66.6
53.3
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
8
8
8
0
0
0
16
47
0
54
31
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
8
0
0
0
% C
% Asp:
24
0
0
0
0
0
39
0
0
39
0
0
0
0
0
% D
% Glu:
8
0
0
0
0
0
47
0
0
47
70
0
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
93
0
0
0
0
8
0
8
8
0
0
16
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
8
0
8
0
0
% H
% Ile:
0
0
0
77
0
0
0
0
93
0
0
0
0
0
8
% I
% Lys:
0
0
0
0
0
0
0
16
0
0
0
0
0
0
0
% K
% Leu:
0
0
8
0
0
0
0
16
0
0
0
16
0
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
16
0
0
0
% M
% Asn:
24
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% N
% Pro:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
39
0
0
0
93
0
8
0
0
0
0
0
0
0
% Q
% Arg:
8
54
0
0
0
0
0
0
0
0
0
0
93
0
0
% R
% Ser:
0
0
0
0
0
0
8
39
0
0
0
0
0
16
16
% S
% Thr:
16
0
0
0
93
0
0
8
0
0
0
16
0
0
0
% T
% Val:
0
0
0
16
0
0
0
0
0
0
0
0
0
0
39
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _