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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP1R16A
All Species:
22.12
Human Site:
S333
Identified Species:
40.56
UniProt:
Q96I34
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96I34
NP_116291.1
528
57811
S333
R
A
Q
S
R
Q
R
S
L
L
R
R
R
T
S
Chimpanzee
Pan troglodytes
XP_528270
444
49041
T255
R
S
L
L
R
R
R
T
S
S
A
G
S
R
G
Rhesus Macaque
Macaca mulatta
XP_001093496
528
57587
S333
R
A
Q
G
R
Q
R
S
L
L
R
R
R
T
S
Dog
Lupus familis
XP_539220
524
57478
S333
R
A
Q
G
R
Q
R
S
L
L
R
R
R
T
S
Cat
Felis silvestris
Mouse
Mus musculus
Q923M0
524
57511
S333
R
A
Q
G
R
Q
R
S
L
L
R
R
R
T
S
Rat
Rattus norvegicus
NP_001124038
525
57775
S334
R
A
Q
G
R
Q
R
S
L
L
R
R
R
T
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518754
485
52245
H319
A
K
L
L
E
L
K
H
K
Q
D
A
I
L
R
Chicken
Gallus gallus
NP_001026022
571
63240
S329
K
S
Q
M
R
H
K
S
S
L
S
R
R
T
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001334473
553
60118
N329
K
G
Q
D
K
H
K
N
T
L
Q
R
R
V
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649049
741
80592
R379
K
R
L
A
E
A
Q
R
R
R
V
R
R
S
Q
Honey Bee
Apis mellifera
XP_395019
523
58785
G321
K
R
L
R
E
A
Q
G
R
R
V
R
R
S
Q
Nematode Worm
Caenorhab. elegans
NP_492587
480
54271
R312
Q
T
E
A
R
R
R
R
L
A
F
G
V
R
D
Sea Urchin
Strong. purpuratus
XP_800118
682
76126
G327
S
N
R
I
R
P
S
G
G
L
V
R
R
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.5
96.5
84
N.A.
82.3
82.9
N.A.
66.6
46.9
N.A.
55.3
N.A.
33
40.1
34.4
33.2
Protein Similarity:
100
83.9
97.3
88.6
N.A.
88
88.6
N.A.
74.6
60.9
N.A.
68.9
N.A.
45.2
58.3
52
49.4
P-Site Identity:
100
20
93.3
93.3
N.A.
93.3
93.3
N.A.
0
53.3
N.A.
33.3
N.A.
13.3
13.3
20
33.3
P-Site Similarity:
100
40
93.3
93.3
N.A.
93.3
93.3
N.A.
6.6
73.3
N.A.
66.6
N.A.
40
33.3
46.6
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
39
0
16
0
16
0
0
0
8
8
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
0
0
0
0
8
0
0
0
8
% D
% Glu:
0
0
8
0
24
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% F
% Gly:
0
8
0
31
0
0
0
16
8
0
0
16
0
0
8
% G
% His:
0
0
0
0
0
16
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
0
0
0
0
0
8
0
0
% I
% Lys:
31
8
0
0
8
0
24
0
8
0
0
0
0
0
0
% K
% Leu:
0
0
31
16
0
8
0
0
47
62
0
0
0
8
0
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
54
0
0
39
16
0
0
8
8
0
0
0
16
% Q
% Arg:
47
16
8
8
70
16
54
16
16
16
39
77
77
16
8
% R
% Ser:
8
16
0
8
0
0
8
47
16
8
8
0
8
24
62
% S
% Thr:
0
8
0
0
0
0
0
8
8
0
0
0
0
47
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
24
0
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _