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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPP1R16A All Species: 21.82
Human Site: S425 Identified Species: 40
UniProt: Q96I34 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96I34 NP_116291.1 528 57811 S425 S P V R H L Y S K R L D R S V
Chimpanzee Pan troglodytes XP_528270 444 49041 S341 S P V R H L Y S K R L D R S V
Rhesus Macaque Macaca mulatta XP_001093496 528 57587 S425 S P A R H L Y S K R L D R S V
Dog Lupus familis XP_539220 524 57478 S425 S P G R H L Y S K R L D R S V
Cat Felis silvestris
Mouse Mus musculus Q923M0 524 57511 S424 P P G R H L Y S K R L D R S V
Rat Rattus norvegicus NP_001124038 525 57775 S425 P P G R H L Y S K R L D R S V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518754 485 52245 T400 S V S Y Q L A T H D P P A P G
Chicken Gallus gallus NP_001026022 571 63240 G453 S M H A D P D G N P G H V L P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001334473 553 60118 G435 F S G E L Q S G G L M D R S A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649049 741 80592 L586 H Q Q H V L L L Q Q H Q Q L Q
Honey Bee Apis mellifera XP_395019 523 58785 P427 E S V T G S D P P I G N Q Q Q
Nematode Worm Caenorhab. elegans NP_492587 480 54271 G393 A D V H S S Q G S L Q H Q R E
Sea Urchin Strong. purpuratus XP_800118 682 76126 E539 E E E Q R K R E E M M R K E N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 83.5 96.5 84 N.A. 82.3 82.9 N.A. 66.6 46.9 N.A. 55.3 N.A. 33 40.1 34.4 33.2
Protein Similarity: 100 83.9 97.3 88.6 N.A. 88 88.6 N.A. 74.6 60.9 N.A. 68.9 N.A. 45.2 58.3 52 49.4
P-Site Identity: 100 100 93.3 93.3 N.A. 86.6 86.6 N.A. 13.3 6.6 N.A. 20 N.A. 6.6 6.6 6.6 0
P-Site Similarity: 100 100 93.3 93.3 N.A. 86.6 86.6 N.A. 20 6.6 N.A. 26.6 N.A. 26.6 20 20 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 8 8 0 0 8 0 0 0 0 0 8 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 8 0 16 0 0 8 0 54 0 0 0 % D
% Glu: 16 8 8 8 0 0 0 8 8 0 0 0 0 8 8 % E
% Phe: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 31 0 8 0 0 24 8 0 16 0 0 0 8 % G
% His: 8 0 8 16 47 0 0 0 8 0 8 16 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 8 0 0 47 0 0 0 8 0 0 % K
% Leu: 0 0 0 0 8 62 8 8 0 16 47 0 0 16 0 % L
% Met: 0 8 0 0 0 0 0 0 0 8 16 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 8 0 0 8 0 0 8 % N
% Pro: 16 47 0 0 0 8 0 8 8 8 8 8 0 8 8 % P
% Gln: 0 8 8 8 8 8 8 0 8 8 8 8 24 8 16 % Q
% Arg: 0 0 0 47 8 0 8 0 0 47 0 8 54 8 0 % R
% Ser: 47 16 8 0 8 16 8 47 8 0 0 0 0 54 0 % S
% Thr: 0 0 0 8 0 0 0 8 0 0 0 0 0 0 0 % T
% Val: 0 8 31 0 8 0 0 0 0 0 0 0 8 0 47 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 0 0 47 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _