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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP1R16A
All Species:
25.76
Human Site:
S433
Identified Species:
47.22
UniProt:
Q96I34
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96I34
NP_116291.1
528
57811
S433
K
R
L
D
R
S
V
S
Y
Q
L
S
P
L
D
Chimpanzee
Pan troglodytes
XP_528270
444
49041
S349
K
R
L
D
R
S
V
S
Y
Q
L
S
P
L
D
Rhesus Macaque
Macaca mulatta
XP_001093496
528
57587
S433
K
R
L
D
R
S
V
S
Y
Q
L
S
S
L
D
Dog
Lupus familis
XP_539220
524
57478
S433
K
R
L
D
R
S
V
S
Y
Q
L
S
P
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q923M0
524
57511
S432
K
R
L
D
R
S
V
S
Y
H
L
S
P
E
E
Rat
Rattus norvegicus
NP_001124038
525
57775
S433
K
R
L
D
R
S
V
S
Y
H
L
S
P
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518754
485
52245
A408
H
D
P
P
A
P
G
A
L
A
R
S
K
A
H
Chicken
Gallus gallus
NP_001026022
571
63240
Y461
N
P
G
H
V
L
P
Y
G
S
P
A
L
P
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001334473
553
60118
S443
G
L
M
D
R
S
A
S
Y
Q
L
S
P
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649049
741
80592
Q594
Q
Q
H
Q
Q
L
Q
Q
H
Q
Q
Q
Q
Q
Q
Honey Bee
Apis mellifera
XP_395019
523
58785
I435
P
I
G
N
Q
Q
Q
I
Y
A
S
D
G
D
T
Nematode Worm
Caenorhab. elegans
NP_492587
480
54271
S401
S
L
Q
H
Q
R
E
S
P
S
K
R
V
L
K
Sea Urchin
Strong. purpuratus
XP_800118
682
76126
A547
E
M
M
R
K
E
N
A
K
P
A
S
P
S
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.5
96.5
84
N.A.
82.3
82.9
N.A.
66.6
46.9
N.A.
55.3
N.A.
33
40.1
34.4
33.2
Protein Similarity:
100
83.9
97.3
88.6
N.A.
88
88.6
N.A.
74.6
60.9
N.A.
68.9
N.A.
45.2
58.3
52
49.4
P-Site Identity:
100
100
93.3
93.3
N.A.
80
80
N.A.
6.6
6.6
N.A.
60
N.A.
6.6
6.6
13.3
13.3
P-Site Similarity:
100
100
93.3
100
N.A.
86.6
86.6
N.A.
13.3
13.3
N.A.
66.6
N.A.
33.3
20
20
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
8
16
0
16
8
8
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
54
0
0
0
0
0
0
0
8
0
8
31
% D
% Glu:
8
0
0
0
0
8
8
0
0
0
0
0
0
16
24
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
16
0
0
0
8
0
8
0
0
0
8
8
8
% G
% His:
8
0
8
16
0
0
0
0
8
16
0
0
0
0
8
% H
% Ile:
0
8
0
0
0
0
0
8
0
0
0
0
0
0
0
% I
% Lys:
47
0
0
0
8
0
0
0
8
0
8
0
8
0
8
% K
% Leu:
0
16
47
0
0
16
0
0
8
0
54
0
8
39
0
% L
% Met:
0
8
16
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
8
0
0
8
0
0
0
0
0
0
0
0
% N
% Pro:
8
8
8
8
0
8
8
0
8
8
8
0
54
8
0
% P
% Gln:
8
8
8
8
24
8
16
8
0
47
8
8
8
8
8
% Q
% Arg:
0
47
0
8
54
8
0
0
0
0
8
8
0
0
0
% R
% Ser:
8
0
0
0
0
54
0
62
0
16
8
70
8
8
8
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% T
% Val:
0
0
0
0
8
0
47
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
62
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _