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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WBSCR16 All Species: 23.33
Human Site: Y157 Identified Species: 39.49
UniProt: Q96I51 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96I51 NP_110425.1 464 49997 Y157 D K T R G Y E Y V L E P S P V
Chimpanzee Pan troglodytes XP_001153683 464 49909 Y157 D K M R G Y E Y V L E P S P V
Rhesus Macaque Macaca mulatta XP_001084290 468 50697 Y157 D K T R G Y E Y V L E P S P V
Dog Lupus familis XP_546911 499 53228 Y192 D K T R G Y E Y V L E P S P V
Cat Felis silvestris
Mouse Mus musculus Q9CYF5 461 49976 Y154 D K T R G Y E Y V L E P S P V
Rat Rattus norvegicus Q6P798 551 60104 S188 S G Q V G S G S T A N Q P I P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001006212 454 49344 Y148 D R T K G Y E Y V L E P S P I
Frog Xenopus laevis Q52KW8 513 55477 G176 D K G Q L G H G D I K R I D V
Zebra Danio Brachydanio rerio Q6NYE2 495 54133 G158 D K G Q L G H G D T K R L E A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608550 454 49701 T153 L P R V Q G E T D E D M R V K
Honey Bee Apis mellifera XP_395025 443 48592 P142 G L I T E P R P I N L P I K D
Nematode Worm Caenorhab. elegans NP_001021671 404 43568 P120 S A K K I N I P G D E I L E I
Sea Urchin Strong. purpuratus XP_001193926 455 49966 R170 N S H G Q C G R P I I P L E D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P21827 482 52995 I153 L E S T P A K I P R E S F P P
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 91.8 80.9 N.A. 90 21 N.A. N.A. 70.6 20.4 20.6 N.A. 39.8 40.7 29.5 46.1
Protein Similarity: 100 99.5 94.4 85.1 N.A. 93.7 35.9 N.A. N.A. 82.7 37.2 37.3 N.A. 59.2 58.6 47.6 64.2
P-Site Identity: 100 93.3 100 100 N.A. 100 6.6 N.A. N.A. 80 20 13.3 N.A. 6.6 6.6 6.6 6.6
P-Site Similarity: 100 93.3 100 100 N.A. 100 6.6 N.A. N.A. 100 40 26.6 N.A. 13.3 13.3 20 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.7 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 38.5 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 0 8 0 0 0 8 0 0 0 0 8 % A
% Cys: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % C
% Asp: 58 0 0 0 0 0 0 0 22 8 8 0 0 8 15 % D
% Glu: 0 8 0 0 8 0 50 0 0 8 58 0 0 22 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % F
% Gly: 8 8 15 8 50 22 15 15 8 0 0 0 0 0 0 % G
% His: 0 0 8 0 0 0 15 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 8 0 8 0 8 8 8 15 8 8 15 8 15 % I
% Lys: 0 50 8 15 0 0 8 0 0 0 15 0 0 8 8 % K
% Leu: 15 8 0 0 15 0 0 0 0 43 8 0 22 0 0 % L
% Met: 0 0 8 0 0 0 0 0 0 0 0 8 0 0 0 % M
% Asn: 8 0 0 0 0 8 0 0 0 8 8 0 0 0 0 % N
% Pro: 0 8 0 0 8 8 0 15 15 0 0 58 8 50 15 % P
% Gln: 0 0 8 15 15 0 0 0 0 0 0 8 0 0 0 % Q
% Arg: 0 8 8 36 0 0 8 8 0 8 0 15 8 0 0 % R
% Ser: 15 8 8 0 0 8 0 8 0 0 0 8 43 0 0 % S
% Thr: 0 0 36 15 0 0 0 8 8 8 0 0 0 0 0 % T
% Val: 0 0 0 15 0 0 0 0 43 0 0 0 0 8 43 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 43 0 43 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _