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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: REXON All Species: 22.73
Human Site: Y603 Identified Species: 62.5
UniProt: Q96IC2 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96IC2 NP_001138396.1 774 86886 Y603 S E N Q G S I Y L S G V S E T
Chimpanzee Pan troglodytes XP_001158166 774 86983 Y603 S E N Q G S I Y L S G V S E T
Rhesus Macaque Macaca mulatta XP_001088611 772 87080 Y603 S E N Q G S I Y L F G V S E T
Dog Lupus familis XP_536947 775 87550 Y604 S E N R G T I Y L S G V S E T
Cat Felis silvestris
Mouse Mus musculus NP_082405 445 50243 K290 E E M K N S M K T K W T Q M S
Rat Rattus norvegicus A1A5R7 754 86034 Y586 S E N Q G T I Y V A G I G E T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001006573 773 85347 Y606 I E N E G V I Y V A G I K K S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8L7M4 567 62783 S412 V K R Y A S E S S N A I P V S
Baker's Yeast Sacchar. cerevisiae P53331 553 62831 R398 N L F T K L H R F E V K T V L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 95.7 84.7 N.A. 41.8 69.1 N.A. N.A. 46.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.4 97.5 92 N.A. 49.8 81.4 N.A. N.A. 63.5 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 93.3 86.6 N.A. 13.3 66.6 N.A. N.A. 40 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 93.3 100 N.A. 33.3 93.3 N.A. N.A. 80 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 23.2 22.2 N.A.
Protein Similarity: N.A. N.A. N.A. 37.8 37.4 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 12 0 0 0 0 23 12 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 12 78 0 12 0 0 12 0 0 12 0 0 0 56 0 % E
% Phe: 0 0 12 0 0 0 0 0 12 12 0 0 0 0 0 % F
% Gly: 0 0 0 0 67 0 0 0 0 0 67 0 12 0 0 % G
% His: 0 0 0 0 0 0 12 0 0 0 0 0 0 0 0 % H
% Ile: 12 0 0 0 0 0 67 0 0 0 0 34 0 0 0 % I
% Lys: 0 12 0 12 12 0 0 12 0 12 0 12 12 12 0 % K
% Leu: 0 12 0 0 0 12 0 0 45 0 0 0 0 0 12 % L
% Met: 0 0 12 0 0 0 12 0 0 0 0 0 0 12 0 % M
% Asn: 12 0 67 0 12 0 0 0 0 12 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 12 0 0 % P
% Gln: 0 0 0 45 0 0 0 0 0 0 0 0 12 0 0 % Q
% Arg: 0 0 12 12 0 0 0 12 0 0 0 0 0 0 0 % R
% Ser: 56 0 0 0 0 56 0 12 12 34 0 0 45 0 34 % S
% Thr: 0 0 0 12 0 23 0 0 12 0 0 12 12 0 56 % T
% Val: 12 0 0 0 0 12 0 0 23 0 12 45 0 23 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 12 0 0 0 0 % W
% Tyr: 0 0 0 12 0 0 0 67 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _