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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXL20
All Species:
37.27
Human Site:
S251
Identified Species:
58.57
UniProt:
Q96IG2
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96IG2
NP_116264.2
436
48423
S251
R
G
C
H
K
L
Q
S
L
C
A
S
G
C
S
Chimpanzee
Pan troglodytes
XP_511453
406
45074
S251
R
G
C
H
K
L
Q
S
L
C
A
S
G
C
S
Rhesus Macaque
Macaca mulatta
XP_001085981
393
43556
I234
Q
N
C
P
R
L
R
I
L
E
V
A
R
C
S
Dog
Lupus familis
XP_850563
524
57716
S339
R
G
C
H
K
L
Q
S
L
C
A
S
G
C
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9CZV8
436
48378
S251
R
G
C
H
K
L
Q
S
L
C
A
S
G
C
S
Rat
Rattus norvegicus
Q9QZH7
276
30442
L122
N
C
R
N
I
E
V
L
S
L
N
G
C
T
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510971
414
45752
S229
R
G
C
H
K
L
Q
S
L
C
A
S
G
C
S
Chicken
Gallus gallus
XP_001235091
441
48786
S256
R
G
C
H
K
L
Q
S
L
C
A
S
G
C
C
Frog
Xenopus laevis
NP_001087065
436
48338
S251
R
G
C
H
K
L
Q
S
L
C
A
S
G
C
A
Zebra Danio
Brachydanio rerio
Q0P4D1
249
27093
S95
R
G
C
A
E
I
T
S
E
G
L
E
V
L
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001097271
651
69789
K466
A
N
C
H
K
L
Q
K
L
C
V
S
K
C
A
Honey Bee
Apis mellifera
XP_393319
435
48744
Y249
E
Q
C
P
R
L
H
Y
V
C
L
S
N
C
P
Nematode Worm
Caenorhab. elegans
P34284
466
52046
Y283
N
G
A
T
A
L
E
Y
L
C
M
S
N
C
N
Sea Urchin
Strong. purpuratus
XP_793918
431
47596
S246
K
G
C
R
T
L
Q
S
L
C
V
S
G
C
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C5D2
610
66404
I402
K
G
C
K
S
L
E
I
L
H
L
V
D
C
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.6
87.8
83.2
N.A.
99.7
62.8
N.A.
92.1
93.8
93.1
22
N.A.
39.1
62.3
45
63
Protein Similarity:
100
93.1
88.7
83.2
N.A.
100
63.2
N.A.
94
95.4
97.4
34.8
N.A.
50.8
77.2
64.8
79.1
P-Site Identity:
100
100
33.3
100
N.A.
100
0
N.A.
100
93.3
93.3
26.6
N.A.
60
33.3
40
66.6
P-Site Similarity:
100
100
60
100
N.A.
100
6.6
N.A.
100
93.3
100
46.6
N.A.
66.6
46.6
53.3
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
7
7
7
0
0
0
0
0
47
7
0
0
20
% A
% Cys:
0
7
87
0
0
0
0
0
0
74
0
0
7
87
7
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% D
% Glu:
7
0
0
0
7
7
14
0
7
7
0
7
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
74
0
0
0
0
0
0
0
7
0
7
54
0
0
% G
% His:
0
0
0
54
0
0
7
0
0
7
0
0
0
0
0
% H
% Ile:
0
0
0
0
7
7
0
14
0
0
0
0
0
0
0
% I
% Lys:
14
0
0
7
54
0
0
7
0
0
0
0
7
0
7
% K
% Leu:
0
0
0
0
0
87
0
7
80
7
20
0
0
7
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% M
% Asn:
14
14
0
7
0
0
0
0
0
0
7
0
14
0
7
% N
% Pro:
0
0
0
14
0
0
0
0
0
0
0
0
0
0
7
% P
% Gln:
7
7
0
0
0
0
60
0
0
0
0
0
0
0
0
% Q
% Arg:
54
0
7
7
14
0
7
0
0
0
0
0
7
0
0
% R
% Ser:
0
0
0
0
7
0
0
60
7
0
0
74
0
0
47
% S
% Thr:
0
0
0
7
7
0
7
0
0
0
0
0
0
7
7
% T
% Val:
0
0
0
0
0
0
7
0
7
0
20
7
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
14
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _