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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FBXL20 All Species: 45.15
Human Site: Y412 Identified Species: 70.95
UniProt: Q96IG2 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96IG2 NP_116264.2 436 48423 Y412 P N I K V H A Y F A P V T P P
Chimpanzee Pan troglodytes XP_511453 406 45074 L386 H S L E R I E L Y D C Q Q I T
Rhesus Macaque Macaca mulatta XP_001085981 393 43556 Y369 P N I K V H A Y F A P V T P P
Dog Lupus familis XP_850563 524 57716 Y500 P N I K V H A Y F A P V T P P
Cat Felis silvestris
Mouse Mus musculus Q9CZV8 436 48378 Y412 P N I K V H A Y F A P V T P P
Rat Rattus norvegicus Q9QZH7 276 30442 G256 L Q S L C A S G C S N I T D A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510971 414 45752 Y390 P N I K V H A Y F A P V T P P
Chicken Gallus gallus XP_001235091 441 48786 Y417 P N I K V H A Y F A P V T P P
Frog Xenopus laevis NP_001087065 436 48338 Y412 P N I K V H A Y F A P V T P P
Zebra Danio Brachydanio rerio Q0P4D1 249 27093 R229 P L I T D K S R E A L Q N L I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001097271 651 69789 Y627 P N I K V H A Y F A P G T P P
Honey Bee Apis mellifera XP_393319 435 48744 Y411 P N I K V H A Y F A P V T P P
Nematode Worm Caenorhab. elegans P34284 466 52046 Y442 P N I E I H A Y F A P V T P P
Sea Urchin Strong. purpuratus XP_793918 431 47596 Y407 P N V K V H A Y F A P V T P P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9C5D2 610 66404 I586 P H I K K V L I E K W K V T E
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 92.6 87.8 83.2 N.A. 99.7 62.8 N.A. 92.1 93.8 93.1 22 N.A. 39.1 62.3 45 63
Protein Similarity: 100 93.1 88.7 83.2 N.A. 100 63.2 N.A. 94 95.4 97.4 34.8 N.A. 50.8 77.2 64.8 79.1
P-Site Identity: 100 0 100 100 N.A. 100 6.6 N.A. 100 100 100 20 N.A. 93.3 100 86.6 93.3
P-Site Similarity: 100 26.6 100 100 N.A. 100 26.6 N.A. 100 100 100 26.6 N.A. 93.3 100 100 100
Percent
Protein Identity: N.A. N.A. N.A. 24.1 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 37.7 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 20 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 7 74 0 0 80 0 0 0 0 7 % A
% Cys: 0 0 0 0 7 0 0 0 7 0 7 0 0 0 0 % C
% Asp: 0 0 0 0 7 0 0 0 0 7 0 0 0 7 0 % D
% Glu: 0 0 0 14 0 0 7 0 14 0 0 0 0 0 7 % E
% Phe: 0 0 0 0 0 0 0 0 74 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 7 0 0 0 7 0 0 0 % G
% His: 7 7 0 0 0 74 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 80 0 7 7 0 7 0 0 0 7 0 7 7 % I
% Lys: 0 0 0 74 7 7 0 0 0 7 0 7 0 0 0 % K
% Leu: 7 7 7 7 0 0 7 7 0 0 7 0 0 7 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 74 0 0 0 0 0 0 0 0 7 0 7 0 0 % N
% Pro: 87 0 0 0 0 0 0 0 0 0 74 0 0 74 74 % P
% Gln: 0 7 0 0 0 0 0 0 0 0 0 14 7 0 0 % Q
% Arg: 0 0 0 0 7 0 0 7 0 0 0 0 0 0 0 % R
% Ser: 0 7 7 0 0 0 14 0 0 7 0 0 0 0 0 % S
% Thr: 0 0 0 7 0 0 0 0 0 0 0 0 80 7 7 % T
% Val: 0 0 7 0 67 7 0 0 0 0 0 67 7 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 74 7 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _