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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HPDL
All Species:
17.58
Human Site:
T175
Identified Species:
32.22
UniProt:
Q96IR7
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96IR7
NP_116145.1
371
39386
T175
C
T
P
G
S
S
P
T
L
L
R
W
F
H
D
Chimpanzee
Pan troglodytes
XP_524567
371
39368
T175
C
T
P
G
S
S
P
T
L
L
R
W
F
H
D
Rhesus Macaque
Macaca mulatta
XP_001100445
381
40428
T175
C
T
A
G
S
S
P
T
L
L
R
W
F
H
N
Dog
Lupus familis
XP_539633
399
42418
T175
C
T
P
G
S
S
P
T
L
M
R
W
F
R
H
Cat
Felis silvestris
Mouse
Mus musculus
Q8K248
371
39891
M175
C
T
S
G
S
S
P
M
L
M
R
W
F
H
D
Rat
Rattus norvegicus
Q5XIH9
371
40014
T175
C
T
S
G
S
S
P
T
L
M
R
W
F
H
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_426651
387
41725
T180
Y
V
C
P
R
G
G
T
Q
A
A
L
E
W
Y
Frog
Xenopus laevis
NP_001085702
391
43668
T182
A
Y
T
C
P
R
G
T
S
P
S
I
L
E
W
Zebra Danio
Brachydanio rerio
Q6TGZ5
397
45192
P190
D
H
I
V
G
N
Q
P
D
D
E
M
V
P
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22633
393
44365
P188
D
H
C
V
G
N
Q
P
D
L
Q
M
D
S
A
Sea Urchin
Strong. purpuratus
XP_001182551
270
30553
M109
R
P
K
K
G
T
N
M
M
F
V
V
A
E
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P93836
445
48797
V185
E
V
K
L
Y
G
D
V
V
L
R
Y
V
S
Y
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q872T7
412
46010
W219
H
C
V
G
N
Q
D
W
N
E
M
V
S
A
C
Conservation
Percent
Protein Identity:
100
99.7
92.9
78.4
N.A.
78.7
79.5
N.A.
N.A.
48.5
40.1
27.9
N.A.
N.A.
N.A.
26.7
30.7
Protein Similarity:
100
100
94.7
83.7
N.A.
85.1
85.7
N.A.
N.A.
62.7
57.2
45.8
N.A.
N.A.
N.A.
43.2
46
P-Site Identity:
100
100
86.6
80
N.A.
80
80
N.A.
N.A.
6.6
6.6
0
N.A.
N.A.
N.A.
6.6
0
P-Site Similarity:
100
100
93.3
86.6
N.A.
86.6
93.3
N.A.
N.A.
6.6
6.6
6.6
N.A.
N.A.
N.A.
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.1
N.A.
20.1
Protein Similarity:
N.A.
N.A.
N.A.
37.3
N.A.
38.8
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
0
0
0
0
0
8
8
0
8
8
16
% A
% Cys:
47
8
16
8
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
16
0
0
0
0
0
16
0
16
8
0
0
8
0
24
% D
% Glu:
8
0
0
0
0
0
0
0
0
8
8
0
8
16
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
0
0
47
0
0
% F
% Gly:
0
0
0
54
24
16
16
0
0
0
0
0
0
0
0
% G
% His:
8
16
0
0
0
0
0
0
0
0
0
0
0
39
8
% H
% Ile:
0
0
8
0
0
0
0
0
0
0
0
8
0
0
0
% I
% Lys:
0
0
16
8
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
8
0
0
0
0
47
39
0
8
8
0
0
% L
% Met:
0
0
0
0
0
0
0
16
8
24
8
16
0
0
0
% M
% Asn:
0
0
0
0
8
16
8
0
8
0
0
0
0
0
16
% N
% Pro:
0
8
24
8
8
0
47
16
0
8
0
0
0
8
0
% P
% Gln:
0
0
0
0
0
8
16
0
8
0
8
0
0
0
0
% Q
% Arg:
8
0
0
0
8
8
0
0
0
0
54
0
0
8
0
% R
% Ser:
0
0
16
0
47
47
0
0
8
0
8
0
8
16
0
% S
% Thr:
0
47
8
0
0
8
0
54
0
0
0
0
0
0
0
% T
% Val:
0
16
8
16
0
0
0
8
8
0
8
16
16
0
8
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
47
0
8
8
% W
% Tyr:
8
8
0
0
8
0
0
0
0
0
0
8
0
0
16
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _