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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NGLY1
All Species:
16.97
Human Site:
S116
Identified Species:
24.89
UniProt:
Q96IV0
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96IV0
NP_001138765.1
654
74390
S116
R
S
S
R
L
D
G
S
N
K
S
H
K
V
K
Chimpanzee
Pan troglodytes
XP_516333
835
93255
S315
R
S
S
R
L
D
G
S
N
K
S
H
K
V
K
Rhesus Macaque
Macaca mulatta
XP_001093251
654
74564
S116
R
S
S
R
L
D
G
S
N
K
S
H
K
L
E
Dog
Lupus familis
XP_534241
2041
231068
S169
R
S
S
R
L
D
G
S
N
K
S
Y
K
V
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9JI78
651
74257
L113
A
I
E
R
S
S
R
L
D
G
S
S
K
K
V
Rat
Rattus norvegicus
Q5XI55
651
74658
L113
A
V
E
R
R
S
R
L
D
G
S
S
Q
K
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507250
647
73725
R110
N
G
S
S
T
G
P
R
G
G
E
S
S
Q
Q
Chicken
Gallus gallus
Q5ZJM3
651
73884
S115
R
S
S
R
L
N
E
S
N
Q
V
H
R
S
A
Frog
Xenopus laevis
NP_001116357
635
72527
A108
R
N
K
R
M
S
A
A
N
P
T
P
P
A
T
Zebra Danio
Brachydanio rerio
Q503I8
644
72470
A109
R
L
G
A
S
N
T
A
S
S
P
Q
N
A
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KRR5
631
73298
W118
L
S
E
R
R
T
A
W
L
N
G
T
V
S
K
Honey Bee
Apis mellifera
XP_392561
589
68873
E84
D
C
L
S
L
P
P
E
A
P
L
S
K
V
Q
Nematode Worm
Caenorhab. elegans
Q9TW67
606
69129
E101
A
N
Q
Q
A
I
A
E
K
I
R
Q
H
Y
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FGY9
721
82428
A157
E
K
A
L
V
S
L
A
K
E
G
N
F
E
P
Baker's Yeast
Sacchar. cerevisiae
Q02890
363
42466
Red Bread Mold
Neurospora crassa
Q7SI01
382
43903
Conservation
Percent
Protein Identity:
100
72.8
96.9
22.5
N.A.
84.5
84.4
N.A.
70.6
68.8
64.2
57.1
N.A.
32.8
35.1
31.3
N.A.
Protein Similarity:
100
74.2
98.9
27.3
N.A.
91.4
90.3
N.A.
81
81.3
78.1
72.6
N.A.
53.2
53
49
N.A.
P-Site Identity:
100
100
86.6
86.6
N.A.
20
13.3
N.A.
6.6
53.3
20
6.6
N.A.
20
20
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
26.6
26.6
N.A.
13.3
73.3
46.6
26.6
N.A.
20
26.6
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.9
25.9
23.2
Protein Similarity:
N.A.
N.A.
N.A.
46.6
37.7
36.3
P-Site Identity:
N.A.
N.A.
N.A.
0
0
0
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
0
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
0
7
7
7
0
19
19
7
0
0
0
0
13
7
% A
% Cys:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
0
0
25
0
0
13
0
0
0
0
0
0
% D
% Glu:
7
0
19
0
0
0
7
13
0
7
7
0
0
7
13
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% F
% Gly:
0
7
7
0
0
7
25
0
7
19
13
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
25
7
0
0
% H
% Ile:
0
7
0
0
0
7
0
0
0
7
0
0
0
0
0
% I
% Lys:
0
7
7
0
0
0
0
0
13
25
0
0
38
13
19
% K
% Leu:
7
7
7
7
38
0
7
13
7
0
7
0
0
7
0
% L
% Met:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
13
0
0
0
13
0
0
38
7
0
7
7
0
0
% N
% Pro:
0
0
0
0
0
7
13
0
0
13
7
7
7
0
7
% P
% Gln:
0
0
7
7
0
0
0
0
0
7
0
13
7
7
13
% Q
% Arg:
44
0
0
57
13
0
13
7
0
0
7
0
7
0
0
% R
% Ser:
0
38
38
13
13
25
0
32
7
7
38
25
7
13
13
% S
% Thr:
0
0
0
0
7
7
7
0
0
0
7
7
0
0
7
% T
% Val:
0
7
0
0
7
0
0
0
0
0
7
0
7
25
13
% V
% Trp:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
7
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _