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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NGLY1
All Species:
18.79
Human Site:
S125
Identified Species:
27.56
UniProt:
Q96IV0
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96IV0
NP_001138765.1
654
74390
S125
K
S
H
K
V
K
S
S
Q
Q
P
A
A
S
T
Chimpanzee
Pan troglodytes
XP_516333
835
93255
S324
K
S
H
K
V
K
S
S
Q
Q
P
A
A
S
T
Rhesus Macaque
Macaca mulatta
XP_001093251
654
74564
S125
K
S
H
K
L
E
S
S
Q
Q
P
A
A
S
T
Dog
Lupus familis
XP_534241
2041
231068
S178
K
S
Y
K
V
E
L
S
Q
Q
P
A
S
S
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9JI78
651
74257
F122
G
S
S
K
K
V
Q
F
S
Q
H
P
A
A
A
Rat
Rattus norvegicus
Q5XI55
651
74658
F122
G
S
S
Q
K
V
E
F
S
Q
H
P
A
A
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507250
647
73725
T119
G
E
S
S
Q
Q
L
T
S
P
N
Q
P
I
L
Chicken
Gallus gallus
Q5ZJM3
651
73884
S124
Q
V
H
R
S
A
S
S
E
T
V
A
I
T
Q
Frog
Xenopus laevis
NP_001116357
635
72527
S117
P
T
P
P
A
T
S
S
T
P
P
A
F
S
R
Zebra Danio
Brachydanio rerio
Q503I8
644
72470
P118
S
P
Q
N
A
S
V
P
P
V
P
A
P
P
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KRR5
631
73298
P127
N
G
T
V
S
K
S
P
P
Q
Q
S
T
T
S
Honey Bee
Apis mellifera
XP_392561
589
68873
L93
P
L
S
K
V
Q
T
L
Q
K
L
L
N
K
N
Nematode Worm
Caenorhab. elegans
Q9TW67
606
69129
T110
I
R
Q
H
Y
S
P
T
P
A
N
P
N
A
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FGY9
721
82428
K166
E
G
N
F
E
P
S
K
E
E
R
D
Y
A
F
Baker's Yeast
Sacchar. cerevisiae
Q02890
363
42466
Red Bread Mold
Neurospora crassa
Q7SI01
382
43903
Conservation
Percent
Protein Identity:
100
72.8
96.9
22.5
N.A.
84.5
84.4
N.A.
70.6
68.8
64.2
57.1
N.A.
32.8
35.1
31.3
N.A.
Protein Similarity:
100
74.2
98.9
27.3
N.A.
91.4
90.3
N.A.
81
81.3
78.1
72.6
N.A.
53.2
53
49
N.A.
P-Site Identity:
100
100
86.6
73.3
N.A.
26.6
20
N.A.
0
26.6
33.3
13.3
N.A.
20
20
0
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
33.3
33.3
N.A.
13.3
53.3
40
13.3
N.A.
40
40
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.9
25.9
23.2
Protein Similarity:
N.A.
N.A.
N.A.
46.6
37.7
36.3
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
0
P-Site Similarity:
N.A.
N.A.
N.A.
40
0
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
13
7
0
0
0
7
0
44
32
25
13
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% D
% Glu:
7
7
0
0
7
13
7
0
13
7
0
0
0
0
0
% E
% Phe:
0
0
0
7
0
0
0
13
0
0
0
0
7
0
7
% F
% Gly:
19
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
25
7
0
0
0
0
0
0
13
0
0
0
0
% H
% Ile:
7
0
0
0
0
0
0
0
0
0
0
0
7
7
0
% I
% Lys:
25
0
0
38
13
19
0
7
0
7
0
0
0
7
0
% K
% Leu:
0
7
0
0
7
0
13
7
0
0
7
7
0
0
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
0
7
7
0
0
0
0
0
0
13
0
13
0
7
% N
% Pro:
13
7
7
7
0
7
7
13
19
13
38
19
13
7
7
% P
% Gln:
7
0
13
7
7
13
7
0
32
44
7
7
0
0
7
% Q
% Arg:
0
7
0
7
0
0
0
0
0
0
7
0
0
0
7
% R
% Ser:
7
38
25
7
13
13
44
38
19
0
0
7
7
32
7
% S
% Thr:
0
7
7
0
0
7
7
13
7
7
0
0
7
13
25
% T
% Val:
0
7
0
7
25
13
7
0
0
7
7
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
7
0
0
0
0
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _