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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NGLY1
All Species:
6.97
Human Site:
S157
Identified Species:
10.22
UniProt:
Q96IV0
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96IV0
NP_001138765.1
654
74390
S157
R
N
R
Q
G
Q
S
S
D
P
P
S
A
S
T
Chimpanzee
Pan troglodytes
XP_516333
835
93255
S356
R
N
R
Q
G
Q
S
S
D
P
P
S
A
S
T
Rhesus Macaque
Macaca mulatta
XP_001093251
654
74564
P157
R
N
R
Q
G
Q
S
P
D
P
P
S
A
S
T
Dog
Lupus familis
XP_534241
2041
231068
S210
A
G
N
S
E
G
Q
S
S
N
P
P
S
A
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9JI78
651
74257
P154
G
N
Q
T
G
Q
L
P
S
L
P
S
A
P
M
Rat
Rattus norvegicus
Q5XI55
651
74658
L154
G
N
Q
P
G
Q
P
L
S
L
P
S
A
P
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507250
647
73725
A151
R
Q
A
S
A
Q
S
A
P
T
P
S
A
S
T
Chicken
Gallus gallus
Q5ZJM3
651
73884
L156
H
Q
Q
P
E
P
S
L
L
Q
S
L
K
M
A
Frog
Xenopus laevis
NP_001116357
635
72527
S149
D
I
S
N
F
L
A
S
E
V
R
Y
L
K
T
Zebra Danio
Brachydanio rerio
Q503I8
644
72470
F150
P
A
P
A
S
I
P
F
T
S
S
S
A
T
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KRR5
631
73298
N159
F
P
R
V
L
R
T
N
N
N
F
L
Q
S
L
Honey Bee
Apis mellifera
XP_392561
589
68873
E125
P
P
T
Y
T
G
E
E
K
N
F
F
K
S
I
Nematode Worm
Caenorhab. elegans
Q9TW67
606
69129
V142
P
R
S
Y
Q
D
E
V
F
K
A
L
A
R
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FGY9
721
82428
N198
P
P
C
D
F
C
G
N
K
T
I
G
Q
G
M
Baker's Yeast
Sacchar. cerevisiae
Q02890
363
42466
Red Bread Mold
Neurospora crassa
Q7SI01
382
43903
Conservation
Percent
Protein Identity:
100
72.8
96.9
22.5
N.A.
84.5
84.4
N.A.
70.6
68.8
64.2
57.1
N.A.
32.8
35.1
31.3
N.A.
Protein Similarity:
100
74.2
98.9
27.3
N.A.
91.4
90.3
N.A.
81
81.3
78.1
72.6
N.A.
53.2
53
49
N.A.
P-Site Identity:
100
100
93.3
13.3
N.A.
40
40
N.A.
53.3
6.6
13.3
13.3
N.A.
13.3
6.6
6.6
N.A.
P-Site Similarity:
100
100
93.3
26.6
N.A.
46.6
46.6
N.A.
60
13.3
26.6
20
N.A.
40
6.6
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.9
25.9
23.2
Protein Similarity:
N.A.
N.A.
N.A.
46.6
37.7
36.3
P-Site Identity:
N.A.
N.A.
N.A.
0
0
0
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
0
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
7
7
7
0
7
7
0
0
7
0
50
7
7
% A
% Cys:
0
0
7
0
0
7
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
7
0
7
0
0
19
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
13
0
13
7
7
0
0
0
0
0
0
% E
% Phe:
7
0
0
0
13
0
0
7
7
0
13
7
0
0
7
% F
% Gly:
13
7
0
0
32
13
7
0
0
0
0
7
0
7
0
% G
% His:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
7
0
0
0
7
0
0
0
0
7
0
0
0
7
% I
% Lys:
0
0
0
0
0
0
0
0
13
7
0
0
13
7
0
% K
% Leu:
0
0
0
0
7
7
7
13
7
13
0
19
7
0
13
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
13
% M
% Asn:
0
32
7
7
0
0
0
13
7
19
0
0
0
0
0
% N
% Pro:
25
19
7
13
0
7
13
13
7
19
44
7
0
13
7
% P
% Gln:
0
13
19
19
7
38
7
0
0
7
0
0
13
0
0
% Q
% Arg:
25
7
25
0
0
7
0
0
0
0
7
0
0
7
0
% R
% Ser:
0
0
13
13
7
0
32
25
19
7
13
44
7
38
7
% S
% Thr:
0
0
7
7
7
0
7
0
7
13
0
0
0
7
32
% T
% Val:
0
0
0
7
0
0
0
7
0
7
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
13
0
0
0
0
0
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _