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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NGLY1
All Species:
29.7
Human Site:
S53
Identified Species:
43.56
UniProt:
Q96IV0
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96IV0
NP_001138765.1
654
74390
S53
P
N
D
E
K
Y
R
S
I
R
I
G
N
T
A
Chimpanzee
Pan troglodytes
XP_516333
835
93255
S252
P
N
D
E
K
Y
R
S
I
R
I
G
N
T
A
Rhesus Macaque
Macaca mulatta
XP_001093251
654
74564
S53
P
N
D
E
K
Y
R
S
I
R
I
G
N
T
A
Dog
Lupus familis
XP_534241
2041
231068
S106
P
N
D
E
K
Y
R
S
I
R
I
G
N
T
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9JI78
651
74257
S53
P
S
D
E
K
Y
R
S
I
R
I
G
N
T
A
Rat
Rattus norvegicus
Q5XI55
651
74658
S53
P
S
D
E
K
Y
R
S
I
R
I
G
N
T
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507250
647
73725
R53
E
N
T
A
F
F
T
R
L
L
P
V
R
G
A
Chicken
Gallus gallus
Q5ZJM3
651
73884
I53
Y
E
E
K
Y
R
S
I
R
N
G
N
P
A
F
Frog
Xenopus laevis
NP_001116357
635
72527
F53
I
R
I
G
N
T
A
F
S
T
R
L
L
P
V
Zebra Danio
Brachydanio rerio
Q503I8
644
72470
T53
I
G
N
P
T
F
S
T
K
L
L
P
V
K
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KRR5
631
73298
T57
P
E
N
S
M
F
R
T
I
R
Q
E
N
K
A
Honey Bee
Apis mellifera
XP_392561
589
68873
T29
D
A
E
N
A
L
L
T
V
C
Q
N
I
L
S
Nematode Worm
Caenorhab. elegans
Q9TW67
606
69129
Q46
M
I
S
P
I
F
E
Q
F
S
A
E
Y
G
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FGY9
721
82428
S64
E
S
D
L
A
S
L
S
E
R
L
R
L
V
S
Baker's Yeast
Sacchar. cerevisiae
Q02890
363
42466
Red Bread Mold
Neurospora crassa
Q7SI01
382
43903
Conservation
Percent
Protein Identity:
100
72.8
96.9
22.5
N.A.
84.5
84.4
N.A.
70.6
68.8
64.2
57.1
N.A.
32.8
35.1
31.3
N.A.
Protein Similarity:
100
74.2
98.9
27.3
N.A.
91.4
90.3
N.A.
81
81.3
78.1
72.6
N.A.
53.2
53
49
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
13.3
0
0
0
N.A.
40
0
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
26.6
13.3
0
26.6
N.A.
60
26.6
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.9
25.9
23.2
Protein Similarity:
N.A.
N.A.
N.A.
46.6
37.7
36.3
P-Site Identity:
N.A.
N.A.
N.A.
20
0
0
P-Site Similarity:
N.A.
N.A.
N.A.
40
0
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
7
13
0
7
0
0
0
7
0
0
7
50
% A
% Cys:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% C
% Asp:
7
0
44
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
13
13
13
38
0
0
7
0
7
0
0
13
0
0
0
% E
% Phe:
0
0
0
0
7
25
0
7
7
0
0
0
0
0
7
% F
% Gly:
0
7
0
7
0
0
0
0
0
0
7
38
0
13
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
13
7
7
0
7
0
0
7
44
0
38
0
7
0
0
% I
% Lys:
0
0
0
7
38
0
0
0
7
0
0
0
0
13
0
% K
% Leu:
0
0
0
7
0
7
13
0
7
13
13
7
13
7
0
% L
% Met:
7
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
32
13
7
7
0
0
0
0
7
0
13
44
0
7
% N
% Pro:
44
0
0
13
0
0
0
0
0
0
7
7
7
7
0
% P
% Gln:
0
0
0
0
0
0
0
7
0
0
13
0
0
0
0
% Q
% Arg:
0
7
0
0
0
7
44
7
7
50
7
7
7
0
0
% R
% Ser:
0
19
7
7
0
7
13
44
7
7
0
0
0
0
13
% S
% Thr:
0
0
7
0
7
7
7
19
0
7
0
0
0
38
0
% T
% Val:
0
0
0
0
0
0
0
0
7
0
0
7
7
7
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
7
38
0
0
0
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _