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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NGLY1
All Species:
33.33
Human Site:
Y375
Identified Species:
48.89
UniProt:
Q96IV0
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96IV0
NP_001138765.1
654
74390
Y375
G
W
G
K
K
L
S
Y
V
I
A
F
S
K
D
Chimpanzee
Pan troglodytes
XP_516333
835
93255
I556
I
G
K
T
F
L
R
I
S
K
R
Q
K
L
I
Rhesus Macaque
Macaca mulatta
XP_001093251
654
74564
Y375
G
W
G
K
K
L
S
Y
V
I
A
F
S
K
D
Dog
Lupus familis
XP_534241
2041
231068
F516
M
N
C
R
E
V
T
F
V
P
G
L
Y
K
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9JI78
651
74257
Y372
G
W
G
K
K
L
S
Y
I
I
A
F
S
K
D
Rat
Rattus norvegicus
Q5XI55
651
74658
Y372
G
W
G
K
K
L
S
Y
I
I
A
F
S
K
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507250
647
73725
Y368
G
W
G
K
K
V
S
Y
I
M
A
F
S
K
D
Chicken
Gallus gallus
Q5ZJM3
651
73884
Y371
G
W
G
K
K
L
S
Y
V
I
A
F
S
K
D
Frog
Xenopus laevis
NP_001116357
635
72527
Y356
G
W
G
K
K
L
S
Y
I
I
A
F
S
K
D
Zebra Danio
Brachydanio rerio
Q503I8
644
72470
Y360
G
W
G
K
K
L
S
Y
I
L
A
F
S
K
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KRR5
631
73298
R358
M
Y
Q
H
G
W
K
R
H
I
D
Y
I
L
A
Honey Bee
Apis mellifera
XP_392561
589
68873
H319
I
H
E
K
K
W
I
H
L
D
P
C
E
D
V
Nematode Worm
Caenorhab. elegans
Q9TW67
606
69129
D336
V
T
W
R
Y
I
W
D
S
K
K
L
V
T
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FGY9
721
82428
S424
F
G
S
D
E
N
S
S
V
S
S
S
S
C
P
Baker's Yeast
Sacchar. cerevisiae
Q02890
363
42466
A93
K
N
V
D
K
E
F
A
K
D
G
H
A
E
G
Red Bread Mold
Neurospora crassa
Q7SI01
382
43903
F112
R
W
F
R
R
S
F
F
T
F
V
N
N
P
P
Conservation
Percent
Protein Identity:
100
72.8
96.9
22.5
N.A.
84.5
84.4
N.A.
70.6
68.8
64.2
57.1
N.A.
32.8
35.1
31.3
N.A.
Protein Similarity:
100
74.2
98.9
27.3
N.A.
91.4
90.3
N.A.
81
81.3
78.1
72.6
N.A.
53.2
53
49
N.A.
P-Site Identity:
100
6.6
100
13.3
N.A.
93.3
93.3
N.A.
80
100
93.3
86.6
N.A.
6.6
13.3
0
N.A.
P-Site Similarity:
100
6.6
100
46.6
N.A.
100
100
N.A.
100
100
100
100
N.A.
20
26.6
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.9
25.9
23.2
Protein Similarity:
N.A.
N.A.
N.A.
46.6
37.7
36.3
P-Site Identity:
N.A.
N.A.
N.A.
20
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
20
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
7
0
0
50
0
7
0
7
% A
% Cys:
0
0
7
0
0
0
0
0
0
0
0
7
0
7
0
% C
% Asp:
0
0
0
13
0
0
0
7
0
13
7
0
0
7
50
% D
% Glu:
0
0
7
0
13
7
0
0
0
0
0
0
7
7
0
% E
% Phe:
7
0
7
0
7
0
13
13
0
7
0
50
0
0
0
% F
% Gly:
50
13
50
0
7
0
0
0
0
0
13
0
0
0
7
% G
% His:
0
7
0
7
0
0
0
7
7
0
0
7
0
0
0
% H
% Ile:
13
0
0
0
0
7
7
7
32
44
0
0
7
0
13
% I
% Lys:
7
0
7
57
63
0
7
0
7
13
7
0
7
57
0
% K
% Leu:
0
0
0
0
0
50
0
0
7
7
0
13
0
13
0
% L
% Met:
13
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% M
% Asn:
0
13
0
0
0
7
0
0
0
0
0
7
7
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
7
7
0
0
7
13
% P
% Gln:
0
0
7
0
0
0
0
0
0
0
0
7
0
0
7
% Q
% Arg:
7
0
0
19
7
0
7
7
0
0
7
0
0
0
0
% R
% Ser:
0
0
7
0
0
7
57
7
13
7
7
7
57
0
0
% S
% Thr:
0
7
0
7
0
0
7
0
7
0
0
0
0
7
0
% T
% Val:
7
0
7
0
0
13
0
0
32
0
7
0
7
0
7
% V
% Trp:
0
57
7
0
0
13
7
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
0
7
0
0
50
0
0
0
7
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _