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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEC22A
All Species:
16.97
Human Site:
S139
Identified Species:
31.11
UniProt:
Q96IW7
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96IW7
NP_036562.2
307
34948
S139
L
S
T
K
I
N
L
S
D
M
Q
T
E
I
K
Chimpanzee
Pan troglodytes
XP_516699
331
36389
E160
S
Y
M
M
L
C
T
E
N
Y
P
N
V
L
A
Rhesus Macaque
Macaca mulatta
XP_001112896
307
34957
S139
L
S
T
K
I
N
L
S
D
M
Q
T
E
I
K
Dog
Lupus familis
XP_850413
303
34347
L138
S
I
Q
M
D
S
S
L
E
K
I
Q
E
E
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BH47
307
35006
S139
L
S
T
K
I
N
L
S
D
M
Q
M
E
I
K
Rat
Rattus norvegicus
Q642F4
307
34883
S139
L
S
T
K
I
N
L
S
D
M
Q
M
E
I
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517497
168
18499
Chicken
Gallus gallus
Q5ZJW4
215
24699
T50
K
L
N
E
Q
S
P
T
R
C
T
L
E
A
G
Frog
Xenopus laevis
NP_001086881
302
34678
N137
R
S
L
S
T
K
M
N
L
A
D
M
Q
T
E
Zebra Danio
Brachydanio rerio
Q7SXP0
215
24671
N50
K
L
N
E
Q
S
P
N
R
C
T
L
E
A
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796488
328
37560
S140
L
N
A
R
Q
K
Y
S
D
M
T
L
E
V
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94AU2
218
25314
M53
G
Q
N
D
A
S
R
M
S
V
E
T
G
P
Y
Baker's Yeast
Sacchar. cerevisiae
P22214
214
25039
A49
T
P
Q
S
A
T
E
A
T
L
E
S
G
S
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.3
99.3
39.4
N.A.
96.7
95.1
N.A.
33.8
28.3
73.2
28.6
N.A.
N.A.
N.A.
N.A.
38.1
Protein Similarity:
100
74.6
99.6
57.9
N.A.
97.7
97.3
N.A.
41
43.9
85.3
45.2
N.A.
N.A.
N.A.
N.A.
57.3
P-Site Identity:
100
0
100
6.6
N.A.
93.3
93.3
N.A.
0
6.6
6.6
6.6
N.A.
N.A.
N.A.
N.A.
40
P-Site Similarity:
100
20
100
20
N.A.
93.3
93.3
N.A.
0
26.6
33.3
26.6
N.A.
N.A.
N.A.
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.7
23.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
42.3
39.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
16
0
0
8
0
8
0
0
0
16
8
% A
% Cys:
0
0
0
0
0
8
0
0
0
16
0
0
0
0
0
% C
% Asp:
0
0
0
8
8
0
0
0
39
0
8
0
0
0
0
% D
% Glu:
0
0
0
16
0
0
8
8
8
0
16
0
62
8
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
8
0
0
0
0
0
0
0
0
0
0
0
16
0
16
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
31
0
0
0
0
0
8
0
0
31
0
% I
% Lys:
16
0
0
31
0
16
0
0
0
8
0
0
0
0
39
% K
% Leu:
39
16
8
0
8
0
31
8
8
8
0
24
0
8
8
% L
% Met:
0
0
8
16
0
0
8
8
0
39
0
24
0
0
0
% M
% Asn:
0
8
24
0
0
31
0
16
8
0
0
8
0
0
0
% N
% Pro:
0
8
0
0
0
0
16
0
0
0
8
0
0
8
0
% P
% Gln:
0
8
16
0
24
0
0
0
0
0
31
8
8
0
0
% Q
% Arg:
8
0
0
8
0
0
8
0
16
0
0
0
0
0
0
% R
% Ser:
16
39
0
16
0
31
8
39
8
0
0
8
0
8
0
% S
% Thr:
8
0
31
0
8
8
8
8
8
0
24
24
0
8
0
% T
% Val:
0
0
0
0
0
0
0
0
0
8
0
0
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
8
0
0
8
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _