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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEC22A
All Species:
13.64
Human Site:
S180
Identified Species:
25
UniProt:
Q96IW7
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96IW7
NP_036562.2
307
34948
S180
K
G
A
G
K
I
S
S
A
H
Q
R
L
E
P
Chimpanzee
Pan troglodytes
XP_516699
331
36389
N201
Y
C
F
I
E
F
D
N
F
I
Q
R
T
K
Q
Rhesus Macaque
Macaca mulatta
XP_001112896
307
34957
S180
K
G
A
G
K
I
S
S
A
H
Q
R
L
E
P
Dog
Lupus familis
XP_850413
303
34347
F179
H
L
E
P
A
P
N
F
R
M
E
P
V
T
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8BH47
307
35006
S180
K
G
A
G
K
I
S
S
A
H
Q
R
L
E
P
Rat
Rattus norvegicus
Q642F4
307
34883
S180
K
G
A
G
K
I
S
S
A
H
Q
R
L
E
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517497
168
18499
P44
L
T
M
A
E
L
A
P
A
N
G
F
P
A
V
Chicken
Gallus gallus
Q5ZJW4
215
24699
L91
A
F
A
Y
L
E
D
L
Q
S
E
F
D
E
Q
Frog
Xenopus laevis
NP_001086881
302
34678
H178
E
Y
K
G
I
A
P
H
Q
R
L
E
P
L
T
Zebra Danio
Brachydanio rerio
Q7SXP0
215
24671
L91
A
F
A
Y
L
E
D
L
Q
A
E
F
H
E
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796488
328
37560
V181
H
I
P
T
W
Q
A
V
N
L
S
D
T
E
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94AU2
218
25314
N94
Q
Y
L
E
D
L
K
N
E
F
E
R
V
N
G
Baker's Yeast
Sacchar. cerevisiae
P22214
214
25039
Q90
S
Y
L
N
D
I
A
Q
E
F
E
H
S
F
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.3
99.3
39.4
N.A.
96.7
95.1
N.A.
33.8
28.3
73.2
28.6
N.A.
N.A.
N.A.
N.A.
38.1
Protein Similarity:
100
74.6
99.6
57.9
N.A.
97.7
97.3
N.A.
41
43.9
85.3
45.2
N.A.
N.A.
N.A.
N.A.
57.3
P-Site Identity:
100
13.3
100
0
N.A.
100
100
N.A.
6.6
13.3
6.6
13.3
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
33.3
100
20
N.A.
100
100
N.A.
33.3
20
13.3
20
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.7
23.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
42.3
39.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
47
8
8
8
24
0
39
8
0
0
0
8
16
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
16
0
24
0
0
0
0
8
8
0
8
% D
% Glu:
8
0
8
8
16
16
0
0
16
0
39
8
0
54
0
% E
% Phe:
0
16
8
0
0
8
0
8
8
16
0
24
0
8
0
% F
% Gly:
0
31
0
39
0
0
0
0
0
0
8
0
0
0
8
% G
% His:
16
0
0
0
0
0
0
8
0
31
0
8
8
0
0
% H
% Ile:
0
8
0
8
8
39
0
0
0
8
0
0
0
0
0
% I
% Lys:
31
0
8
0
31
0
8
0
0
0
0
0
0
8
0
% K
% Leu:
8
8
16
0
16
16
0
16
0
8
8
0
31
8
0
% L
% Met:
0
0
8
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
8
16
8
8
0
0
0
8
0
% N
% Pro:
0
0
8
8
0
8
8
8
0
0
0
8
16
0
31
% P
% Gln:
8
0
0
0
0
8
0
8
24
0
39
0
0
0
24
% Q
% Arg:
0
0
0
0
0
0
0
0
8
8
0
47
0
0
0
% R
% Ser:
8
0
0
0
0
0
31
31
0
8
8
0
8
0
0
% S
% Thr:
0
8
0
8
0
0
0
0
0
0
0
0
16
8
8
% T
% Val:
0
0
0
0
0
0
0
8
0
0
0
0
16
0
8
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
24
0
16
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _