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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEC22A All Species: 13.64
Human Site: S8 Identified Species: 25
UniProt: Q96IW7 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96IW7 NP_036562.2 307 34948 S8 M S M I L S A S V I R V R D G
Chimpanzee Pan troglodytes XP_516699 331 36389 P29 A R A E P D W P G R A E G T G
Rhesus Macaque Macaca mulatta XP_001112896 307 34957 S8 M S M I L S A S V I R V R D G
Dog Lupus familis XP_850413 303 34347
Cat Felis silvestris
Mouse Mus musculus Q8BH47 307 35006 S8 M S M I L S A S V I R V R D G
Rat Rattus norvegicus Q642F4 307 34883 S8 M S M I L S A S V V R V R D G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517497 168 18499
Chicken Gallus gallus Q5ZJW4 215 24699
Frog Xenopus laevis NP_001086881 302 34678
Zebra Danio Brachydanio rerio Q7SXP0 215 24671
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796488 328 37560 M9 S G N V L F A M I T R L R D G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q94AU2 218 25314
Baker's Yeast Sacchar. cerevisiae P22214 214 25039
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 74.3 99.3 39.4 N.A. 96.7 95.1 N.A. 33.8 28.3 73.2 28.6 N.A. N.A. N.A. N.A. 38.1
Protein Similarity: 100 74.6 99.6 57.9 N.A. 97.7 97.3 N.A. 41 43.9 85.3 45.2 N.A. N.A. N.A. N.A. 57.3
P-Site Identity: 100 6.6 100 0 N.A. 100 93.3 N.A. 0 0 0 0 N.A. N.A. N.A. N.A. 40
P-Site Similarity: 100 6.6 100 0 N.A. 100 100 N.A. 0 0 0 0 N.A. N.A. N.A. N.A. 60
Percent
Protein Identity: N.A. N.A. N.A. 24.7 23.1 N.A.
Protein Similarity: N.A. N.A. N.A. 42.3 39.7 N.A.
P-Site Identity: N.A. N.A. N.A. 0 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 0 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 8 0 0 0 39 0 0 0 8 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 8 0 0 0 0 0 0 0 39 0 % D
% Glu: 0 0 0 8 0 0 0 0 0 0 0 8 0 0 0 % E
% Phe: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 8 0 0 0 0 0 0 8 0 0 0 8 0 47 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 31 0 0 0 0 8 24 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 39 0 0 0 0 0 0 8 0 0 0 % L
% Met: 31 0 31 0 0 0 0 8 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 8 0 0 8 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 8 0 0 0 0 0 0 0 8 39 0 39 0 0 % R
% Ser: 8 31 0 0 0 31 0 31 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 8 0 0 0 8 0 % T
% Val: 0 0 0 8 0 0 0 0 31 8 0 31 0 0 0 % V
% Trp: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _