KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEC22A
All Species:
17.88
Human Site:
Y126
Identified Species:
32.78
UniProt:
Q96IW7
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96IW7
NP_036562.2
307
34948
Y126
I
Q
R
T
K
Q
R
Y
N
N
P
R
S
L
S
Chimpanzee
Pan troglodytes
XP_516699
331
36389
I147
G
H
Y
N
I
N
F
I
S
S
L
G
V
S
Y
Rhesus Macaque
Macaca mulatta
XP_001112896
307
34957
Y126
I
Q
R
T
K
Q
R
Y
N
N
P
R
S
L
S
Dog
Lupus familis
XP_850413
303
34347
H125
V
I
Q
K
V
K
W
H
F
N
H
I
S
S
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8BH47
307
35006
Y126
I
Q
R
T
K
Q
R
Y
N
N
P
R
S
L
S
Rat
Rattus norvegicus
Q642F4
307
34883
Y126
I
Q
R
T
K
Q
R
Y
N
N
P
R
S
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517497
168
18499
Chicken
Gallus gallus
Q5ZJW4
215
24699
A37
L
Q
Q
Y
Q
S
Q
A
K
Q
L
F
R
K
L
Frog
Xenopus laevis
NP_001086881
302
34678
Q124
N
F
I
Q
K
T
K
Q
R
F
N
N
P
R
S
Zebra Danio
Brachydanio rerio
Q7SXP0
215
24671
A37
L
Q
Q
Y
Q
S
Q
A
K
Q
L
F
R
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796488
328
37560
Y127
I
Q
K
T
K
Q
R
Y
N
N
P
M
T
L
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94AU2
218
25314
F40
K
Q
Q
V
K
A
L
F
K
N
L
S
R
G
Q
Baker's Yeast
Sacchar. cerevisiae
P22214
214
25039
I36
E
Q
K
Q
K
V
K
I
V
V
S
R
L
T
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.3
99.3
39.4
N.A.
96.7
95.1
N.A.
33.8
28.3
73.2
28.6
N.A.
N.A.
N.A.
N.A.
38.1
Protein Similarity:
100
74.6
99.6
57.9
N.A.
97.7
97.3
N.A.
41
43.9
85.3
45.2
N.A.
N.A.
N.A.
N.A.
57.3
P-Site Identity:
100
0
100
13.3
N.A.
100
100
N.A.
0
6.6
13.3
6.6
N.A.
N.A.
N.A.
N.A.
73.3
P-Site Similarity:
100
13.3
100
40
N.A.
100
100
N.A.
0
33.3
20
33.3
N.A.
N.A.
N.A.
N.A.
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.7
23.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
42.3
39.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
16
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
8
0
0
0
0
8
8
8
8
0
16
0
0
0
% F
% Gly:
8
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% G
% His:
0
8
0
0
0
0
0
8
0
0
8
0
0
0
0
% H
% Ile:
39
8
8
0
8
0
0
16
0
0
0
8
0
0
8
% I
% Lys:
8
0
16
8
62
8
16
0
24
0
0
0
0
16
0
% K
% Leu:
16
0
0
0
0
0
8
0
0
0
31
0
8
39
16
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
8
0
0
8
0
8
0
0
39
54
8
8
0
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
39
0
8
0
8
% P
% Gln:
0
70
31
16
16
39
16
8
0
16
0
0
0
0
8
% Q
% Arg:
0
0
31
0
0
0
39
0
8
0
0
39
24
8
0
% R
% Ser:
0
0
0
0
0
16
0
0
8
8
8
8
39
16
39
% S
% Thr:
0
0
0
39
0
8
0
0
0
0
0
0
8
8
0
% T
% Val:
8
0
0
8
8
8
0
0
8
8
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
16
0
0
0
39
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _