KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEC22A
All Species:
10.91
Human Site:
Y24
Identified Species:
20
UniProt:
Q96IW7
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96IW7
NP_036562.2
307
34948
Y24
P
L
S
A
S
T
D
Y
E
Q
S
T
G
M
Q
Chimpanzee
Pan troglodytes
XP_516699
331
36389
S45
W
F
D
S
A
G
A
S
H
V
G
R
A
A
A
Rhesus Macaque
Macaca mulatta
XP_001112896
307
34957
Y24
P
L
S
A
S
T
D
Y
E
Q
S
T
G
M
Q
Dog
Lupus familis
XP_850413
303
34347
D23
L
P
L
S
A
S
T
D
F
Y
H
T
Q
D
F
Cat
Felis silvestris
Mouse
Mus musculus
Q8BH47
307
35006
Y24
P
L
S
A
S
T
D
Y
E
Q
S
T
G
M
Q
Rat
Rattus norvegicus
Q642F4
307
34883
C24
P
L
S
A
S
T
D
C
E
Q
S
A
G
V
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517497
168
18499
Chicken
Gallus gallus
Q5ZJW4
215
24699
Frog
Xenopus laevis
NP_001086881
302
34678
T22
G
L
P
L
S
A
S
T
D
H
E
Q
N
M
S
Zebra Danio
Brachydanio rerio
Q7SXP0
215
24671
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796488
328
37560
H25
P
L
S
A
T
T
D
H
D
P
S
Q
R
V
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94AU2
218
25314
Baker's Yeast
Sacchar. cerevisiae
P22214
214
25039
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.3
99.3
39.4
N.A.
96.7
95.1
N.A.
33.8
28.3
73.2
28.6
N.A.
N.A.
N.A.
N.A.
38.1
Protein Similarity:
100
74.6
99.6
57.9
N.A.
97.7
97.3
N.A.
41
43.9
85.3
45.2
N.A.
N.A.
N.A.
N.A.
57.3
P-Site Identity:
100
0
100
6.6
N.A.
100
80
N.A.
0
0
20
0
N.A.
N.A.
N.A.
N.A.
46.6
P-Site Similarity:
100
13.3
100
26.6
N.A.
100
86.6
N.A.
0
0
26.6
0
N.A.
N.A.
N.A.
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.7
23.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
42.3
39.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
39
16
8
8
0
0
0
0
8
8
8
8
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
39
8
16
0
0
0
0
8
0
% D
% Glu:
0
0
0
0
0
0
0
0
31
0
8
0
0
0
0
% E
% Phe:
0
8
0
0
0
0
0
0
8
0
0
0
0
0
8
% F
% Gly:
8
0
0
0
0
8
0
0
0
0
8
0
31
0
0
% G
% His:
0
0
0
0
0
0
0
8
8
8
8
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
8
47
8
8
0
0
0
0
0
0
0
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
31
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% N
% Pro:
39
8
8
0
0
0
0
0
0
8
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
31
0
16
8
0
31
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
8
8
0
0
% R
% Ser:
0
0
39
16
39
8
8
8
0
0
39
0
0
0
8
% S
% Thr:
0
0
0
0
8
39
8
8
0
0
0
31
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
8
0
0
0
16
0
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
24
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _