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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
METTL2A
All Species:
34.24
Human Site:
Y314
Identified Species:
62.78
UniProt:
Q96IZ6
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96IZ6
NP_859076.3
378
43537
Y314
Q
C
L
S
G
N
F
Y
V
R
G
D
G
T
R
Chimpanzee
Pan troglodytes
XP_001152439
378
43448
Y314
Q
C
L
S
G
N
F
Y
V
R
G
D
G
T
R
Rhesus Macaque
Macaca mulatta
XP_001116039
379
43675
Y315
Q
C
L
S
G
N
F
Y
V
R
G
D
G
T
R
Dog
Lupus familis
XP_537604
474
53846
Y410
Q
C
L
S
E
N
F
Y
V
R
G
D
G
T
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8BMK1
389
43893
Y307
Q
C
L
S
G
N
F
Y
V
R
G
D
G
T
R
Rat
Rattus norvegicus
Q6AXU8
287
33363
V232
E
F
L
A
K
L
F
V
D
A
G
Y
E
E
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518238
377
41950
Y313
R
C
L
S
E
N
F
Y
V
R
G
D
G
T
R
Chicken
Gallus gallus
Q5ZHP8
370
42711
Y307
Q
C
L
S
A
N
F
Y
V
R
G
D
G
T
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A8KBL7
353
40469
R298
Y
V
R
G
D
G
T
R
V
Y
F
F
T
Q
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q86BS6
325
38113
D270
D
N
F
Y
V
R
G
D
G
T
M
V
Y
F
F
Honey Bee
Apis mellifera
XP_624474
332
39379
R277
L
A
N
N
F
Y
V
R
G
D
G
T
R
V
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001175658
397
45417
Y339
R
C
L
S
E
N
F
Y
V
R
G
D
G
T
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q08641
628
71467
Y569
R
I
L
E
E
N
F
Y
V
R
G
D
G
T
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.1
97.3
71.7
N.A.
78.1
33.8
N.A.
67.7
65.3
N.A.
66.1
N.A.
36.2
50.5
N.A.
43.3
Protein Similarity:
100
98.4
98.1
75.1
N.A.
84.3
46.5
N.A.
76.9
78.3
N.A.
76.4
N.A.
53.7
63.4
N.A.
59.7
P-Site Identity:
100
100
100
93.3
N.A.
100
20
N.A.
86.6
93.3
N.A.
6.6
N.A.
0
6.6
N.A.
86.6
P-Site Similarity:
100
100
100
93.3
N.A.
100
33.3
N.A.
93.3
93.3
N.A.
6.6
N.A.
0
13.3
N.A.
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
37.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
73.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
8
8
0
0
0
0
8
0
0
0
0
0
% A
% Cys:
0
62
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
8
0
0
8
8
8
0
70
0
0
8
% D
% Glu:
8
0
0
8
31
0
0
0
0
0
0
0
8
8
0
% E
% Phe:
0
8
8
0
8
0
77
0
0
0
8
8
0
8
8
% F
% Gly:
0
0
0
8
31
8
8
0
16
0
85
0
70
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
8
0
77
0
0
8
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
8
8
8
0
70
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
47
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% Q
% Arg:
24
0
8
0
0
8
0
16
0
70
0
0
8
0
70
% R
% Ser:
0
0
0
62
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
8
0
0
8
0
8
8
70
0
% T
% Val:
0
8
0
0
8
0
8
8
77
0
0
8
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
8
0
8
0
70
0
8
0
8
8
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _