KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
METTL2A
All Species:
24.85
Human Site:
Y369
Identified Species:
45.56
UniProt:
Q96IZ6
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96IZ6
NP_859076.3
378
43537
Y369
R
V
W
I
Q
C
K
Y
C
K
P
L
L
S
S
Chimpanzee
Pan troglodytes
XP_001152439
378
43448
Y369
R
V
W
I
Q
C
K
Y
C
K
P
L
L
S
S
Rhesus Macaque
Macaca mulatta
XP_001116039
379
43675
Y370
R
V
W
I
Q
C
K
Y
C
K
P
L
L
S
S
Dog
Lupus familis
XP_537604
474
53846
Y465
R
V
W
I
Q
C
K
Y
R
K
P
L
L
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8BMK1
389
43893
Y362
R
V
W
I
Q
C
K
Y
S
K
P
L
A
L
R
Rat
Rattus norvegicus
Q6AXU8
287
33363
S279
D
P
A
P
T
T
D
S
A
S
L
L
R
K
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518238
377
41950
Y368
R
I
W
I
Q
C
R
Y
R
K
P
L
P
S
S
Chicken
Gallus gallus
Q5ZHP8
370
42711
Y362
R
V
W
I
Q
C
K
Y
Q
K
P
A
G
P
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A8KBL7
353
40469
K345
Y
R
V
W
V
Q
C
K
Y
R
K
V
L
A
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q86BS6
325
38113
I317
L
K
M
Y
R
V
W
I
Q
T
K
F
R
K
P
Honey Bee
Apis mellifera
XP_624474
332
39379
V324
K
Q
L
K
M
Y
R
V
W
I
Q
G
K
Y
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001175658
397
45417
W389
Q
L
T
M
Y
R
V
W
I
Q
C
K
Y
R
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q08641
628
71467
Y616
R
K
R
Q
L
K
M
Y
R
C
W
V
Q
A
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.1
97.3
71.7
N.A.
78.1
33.8
N.A.
67.7
65.3
N.A.
66.1
N.A.
36.2
50.5
N.A.
43.3
Protein Similarity:
100
98.4
98.1
75.1
N.A.
84.3
46.5
N.A.
76.9
78.3
N.A.
76.4
N.A.
53.7
63.4
N.A.
59.7
P-Site Identity:
100
100
100
86.6
N.A.
73.3
6.6
N.A.
73.3
66.6
N.A.
6.6
N.A.
0
0
N.A.
0
P-Site Similarity:
100
100
100
86.6
N.A.
73.3
6.6
N.A.
86.6
66.6
N.A.
26.6
N.A.
6.6
13.3
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
37.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
0
8
0
0
8
8
16
0
% A
% Cys:
0
0
0
0
0
54
8
0
24
8
8
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
8
8
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
54
0
0
0
8
8
8
0
0
0
0
0
% I
% Lys:
8
16
0
8
0
8
47
8
0
54
16
8
8
16
8
% K
% Leu:
8
8
8
0
8
0
0
0
0
0
8
54
39
8
0
% L
% Met:
0
0
8
8
8
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
8
0
8
0
0
0
0
0
0
54
0
8
8
16
% P
% Gln:
8
8
0
8
54
8
0
0
16
8
8
0
8
0
8
% Q
% Arg:
62
8
8
0
8
8
16
0
24
8
0
0
16
8
16
% R
% Ser:
0
0
0
0
0
0
0
8
8
8
0
0
0
39
31
% S
% Thr:
0
0
8
0
8
8
0
0
0
8
0
0
0
0
0
% T
% Val:
0
47
8
0
8
8
8
8
0
0
0
16
0
0
8
% V
% Trp:
0
0
54
8
0
0
8
8
8
0
8
0
0
0
0
% W
% Tyr:
8
0
0
8
8
8
0
62
8
0
0
0
8
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _