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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: THOC3 All Species: 13.64
Human Site: S74 Identified Species: 42.86
UniProt: Q96J01 Number Species: 7
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96J01 NP_115737.1 351 38772 S74 G R R L A S G S F D K T A S V
Chimpanzee Pan troglodytes XP_001157097 327 35999 K57 E F L A H S A K V H S V A W S
Rhesus Macaque Macaca mulatta XP_001083412 351 38783 S74 G R R L A S G S F D K T A S V
Dog Lupus familis XP_537899 351 38765 S74 G R R L A S G S F D K T A S V
Cat Felis silvestris
Mouse Mus musculus Q8VE80 351 38719 S74 G R R L A S G S F D K T A S V
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396624 320 35850 V50 S G S F D K S V C I F S L C P
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782363 321 36161 V51 S G S F D R N V S V F S L D R
Poplar Tree Populus trichocarpa XP_002300586 313 35175 A43 S G S V D Q T A R V W H I D L
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 87.1 99.7 99.1 N.A. 98.8 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. 58.9 N.A. 65.5
Protein Similarity: 100 88.8 99.7 99.7 N.A. 99.1 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. 74 N.A. 79.2
P-Site Identity: 100 13.3 100 100 N.A. 100 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. 0 N.A. 0
P-Site Similarity: 100 13.3 100 100 N.A. 100 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. 6.6 N.A. 6.6
Percent
Protein Identity: 45 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 62.3 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 20 N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 13 50 0 13 13 0 0 0 0 63 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 13 0 0 0 0 13 0 % C
% Asp: 0 0 0 0 38 0 0 0 0 50 0 0 0 25 0 % D
% Glu: 13 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 13 0 25 0 0 0 0 50 0 25 0 0 0 0 % F
% Gly: 50 38 0 0 0 0 50 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 13 0 0 0 0 13 0 13 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 13 0 0 13 0 0 % I
% Lys: 0 0 0 0 0 13 0 13 0 0 50 0 0 0 0 % K
% Leu: 0 0 13 50 0 0 0 0 0 0 0 0 25 0 13 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 13 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13 % P
% Gln: 0 0 0 0 0 13 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 50 50 0 0 13 0 0 13 0 0 0 0 0 13 % R
% Ser: 38 0 38 0 0 63 13 50 13 0 13 25 0 50 13 % S
% Thr: 0 0 0 0 0 0 13 0 0 0 0 50 0 0 0 % T
% Val: 0 0 0 13 0 0 0 25 13 25 0 13 0 0 50 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 13 0 0 13 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _