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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABCC12 All Species: 13.64
Human Site: T769 Identified Species: 27.27
UniProt: Q96J65 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.27
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96J65 NP_150229.2 1359 152297 T769 P E H Q L I Q T E S P Q E G T
Chimpanzee Pan troglodytes XP_001163259 1359 152165 T769 P E H Q L I Q T E S P Q E G T
Rhesus Macaque Macaca mulatta XP_001114196 1382 154134 I797 W R V Y H H Y I Q A A G G Y V
Dog Lupus familis XP_544420 1367 152826 T775 P L H Q L V Q T E S P Q E G T
Cat Felis silvestris
Mouse Mus musculus Q80WJ6 1366 153042 T766 P A H Q L I Q T E S P Q E G I
Rat Rattus norvegicus Q6Y306 1366 152946 I766 P V H Q L I Q I E S P Q E G I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507533 1472 164792 R774 P A H Q L V Q R E T T L E G S
Chicken Gallus gallus Q5F364 1525 170953 A927 S Q H Q S S T A E L Q K P L A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_696904 1368 153325 R768 K K D Q L V T R E V A Q E G S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P91660 1290 143990 V708 F Q A G G G L V A F L V M L S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9C8G9 1622 181908 R890 G N S V L V K R E E R E T G V
Baker's Yeast Sacchar. cerevisiae P39109 1515 171103 S908 A I S L R R A S D A T L G S I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.8 48.2 88.1 N.A. 84.7 83.7 N.A. 65.1 29.3 N.A. 52.4 N.A. 30.9 N.A. N.A. N.A.
Protein Similarity: 100 96.7 66.5 93 N.A. 91.2 90.5 N.A. 76.6 49.9 N.A. 70 N.A. 53.1 N.A. N.A. N.A.
P-Site Identity: 100 100 0 86.6 N.A. 86.6 80 N.A. 53.3 20 N.A. 40 N.A. 0 N.A. N.A. N.A.
P-Site Similarity: 100 100 13.3 93.3 N.A. 86.6 80 N.A. 73.3 33.3 N.A. 60 N.A. 13.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 28.7 28.7 N.A.
Protein Similarity: N.A. N.A. N.A. 45.1 48.8 N.A.
P-Site Identity: N.A. N.A. N.A. 20 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 40 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 17 9 0 0 0 9 9 9 17 17 0 0 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 9 0 0 0 0 0 9 0 0 0 0 0 0 % D
% Glu: 0 17 0 0 0 0 0 0 75 9 0 9 59 0 0 % E
% Phe: 9 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % F
% Gly: 9 0 0 9 9 9 0 0 0 0 0 9 17 67 0 % G
% His: 0 0 59 0 9 9 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 9 0 0 0 34 0 17 0 0 0 0 0 0 25 % I
% Lys: 9 9 0 0 0 0 9 0 0 0 0 9 0 0 0 % K
% Leu: 0 9 0 9 67 0 9 0 0 9 9 17 0 17 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % M
% Asn: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 50 0 0 0 0 0 0 0 0 0 42 0 9 0 0 % P
% Gln: 0 17 0 67 0 0 50 0 9 0 9 50 0 0 0 % Q
% Arg: 0 9 0 0 9 9 0 25 0 0 9 0 0 0 0 % R
% Ser: 9 0 17 0 9 9 0 9 0 42 0 0 0 9 25 % S
% Thr: 0 0 0 0 0 0 17 34 0 9 17 0 9 0 25 % T
% Val: 0 9 9 9 0 34 0 9 0 9 0 9 0 0 17 % V
% Trp: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 9 0 0 9 0 0 0 0 0 0 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _