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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABCC12 All Species: 22.08
Human Site: Y7 Identified Species: 44.16
UniProt: Q96J65 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96J65 NP_150229.2 1359 152297 Y7 _ M V G E G P Y L I S D L D Q
Chimpanzee Pan troglodytes XP_001163259 1359 152165 Y7 _ M V G E G P Y L I S D L D Q
Rhesus Macaque Macaca mulatta XP_001114196 1382 154134 D22 G L V N L G I D I G D D M V S
Dog Lupus familis XP_544420 1367 152826 Y7 _ M V G E G P Y L I S D L D R
Cat Felis silvestris
Mouse Mus musculus Q80WJ6 1366 153042 Y7 _ M V G E G P Y L I S D L D R
Rat Rattus norvegicus Q6Y306 1366 152946 Y7 _ M V G E D P Y L I S D L D R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507533 1472 164792 Y7 _ M V G A G P Y L I S D L D K
Chicken Gallus gallus Q5F364 1525 170953 L118 T V L G I T M L L A T F L I Q
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_696904 1368 153325 G32 A M S A F P E G P P V L D Y R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P91660 1290 143990 F12 H S Y I F Y T F S R L F N K Y
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9C8G9 1622 181908 P12 P L D W Y C K P V P N G V W T
Baker's Yeast Sacchar. cerevisiae P39109 1515 171103 F48 S A I F M I T F G I R D L V N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.8 48.2 88.1 N.A. 84.7 83.7 N.A. 65.1 29.3 N.A. 52.4 N.A. 30.9 N.A. N.A. N.A.
Protein Similarity: 100 96.7 66.5 93 N.A. 91.2 90.5 N.A. 76.6 49.9 N.A. 70 N.A. 53.1 N.A. N.A. N.A.
P-Site Identity: 100 100 20 92.8 N.A. 92.8 85.7 N.A. 85.7 26.6 N.A. 6.6 N.A. 0 N.A. N.A. N.A.
P-Site Similarity: 100 100 46.6 100 N.A. 100 92.8 N.A. 92.8 46.6 N.A. 13.3 N.A. 6.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 28.7 28.7 N.A.
Protein Similarity: N.A. N.A. N.A. 45.1 48.8 N.A.
P-Site Identity: N.A. N.A. N.A. 0 20 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 9 0 9 9 0 0 0 0 9 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 9 0 0 9 0 9 0 0 9 67 9 50 0 % D
% Glu: 0 0 0 0 42 0 9 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 9 17 0 0 17 0 0 0 17 0 0 0 % F
% Gly: 9 0 0 59 0 50 0 9 9 9 0 9 0 0 0 % G
% His: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 9 9 9 9 9 0 9 59 0 0 0 9 0 % I
% Lys: 0 0 0 0 0 0 9 0 0 0 0 0 0 9 9 % K
% Leu: 0 17 9 0 9 0 0 9 59 0 9 9 67 0 0 % L
% Met: 0 59 0 0 9 0 9 0 0 0 0 0 9 0 0 % M
% Asn: 0 0 0 9 0 0 0 0 0 0 9 0 9 0 9 % N
% Pro: 9 0 0 0 0 9 50 9 9 17 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 25 % Q
% Arg: 0 0 0 0 0 0 0 0 0 9 9 0 0 0 34 % R
% Ser: 9 9 9 0 0 0 0 0 9 0 50 0 0 0 9 % S
% Thr: 9 0 0 0 0 9 17 0 0 0 9 0 0 0 9 % T
% Val: 0 9 59 0 0 0 0 0 9 0 9 0 9 17 0 % V
% Trp: 0 0 0 9 0 0 0 0 0 0 0 0 0 9 0 % W
% Tyr: 0 0 9 0 9 9 0 50 0 0 0 0 0 9 9 % Y
% Spaces: 50 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _