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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIWIL1
All Species:
29.39
Human Site:
S103
Identified Species:
53.89
UniProt:
Q96J94
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96J94
NP_004755.2
861
98603
S103
N
L
D
H
V
K
E
S
K
T
G
S
S
G
I
Chimpanzee
Pan troglodytes
XP_001137815
861
98509
S103
N
L
D
H
V
K
E
S
K
T
G
S
S
G
I
Rhesus Macaque
Macaca mulatta
XP_001089264
852
96294
C97
K
L
A
H
V
R
D
C
K
T
G
S
S
G
I
Dog
Lupus familis
XP_534638
861
98542
S103
N
L
D
H
V
K
E
S
K
T
G
S
S
G
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9JMB7
862
98556
S104
N
L
D
H
V
K
E
S
K
T
G
S
S
G
I
Rat
Rattus norvegicus
Q4G033
848
95953
S92
K
L
T
H
V
K
D
S
K
T
G
S
S
G
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509070
1180
134396
S422
G
I
E
H
V
Q
E
S
K
T
G
S
S
G
I
Chicken
Gallus gallus
A6N7Y9
867
99268
S111
A
I
E
H
V
R
E
S
K
T
G
S
S
G
A
Frog
Xenopus laevis
Q6DCX2
862
97626
N101
P
V
F
D
G
R
K
N
L
Y
T
A
M
P
L
Zebra Danio
Brachydanio rerio
Q8UVX0
858
97433
S101
L
M
E
H
V
K
E
S
K
T
G
V
S
G
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VKM1
843
97159
G91
A
E
L
V
S
K
K
G
T
D
G
V
P
V
M
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_999765
854
96704
V98
T
T
R
P
E
N
F
V
K
Q
A
I
A
G
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04379
1048
116172
R182
K
A
F
K
F
P
M
R
P
G
K
G
Q
S
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
49.3
95.9
N.A.
94.9
50
N.A.
63.9
77
24.5
64.8
N.A.
35.7
N.A.
N.A.
47.6
Protein Similarity:
100
99.5
67.7
97.9
N.A.
97.4
68
N.A.
69.3
88.1
44.7
80.1
N.A.
57.2
N.A.
N.A.
64.3
P-Site Identity:
100
100
66.6
100
N.A.
100
80
N.A.
73.3
66.6
0
66.6
N.A.
13.3
N.A.
N.A.
13.3
P-Site Similarity:
100
100
80
100
N.A.
100
86.6
N.A.
93.3
86.6
40
80
N.A.
26.6
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.8
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
8
8
0
0
0
0
0
0
0
8
8
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
0
31
8
0
0
16
0
0
8
0
0
0
0
8
% D
% Glu:
0
8
24
0
8
0
54
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
16
0
8
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
8
0
0
8
0
8
77
8
0
77
8
% G
% His:
0
0
0
70
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
16
0
0
0
0
0
0
0
0
0
8
0
0
54
% I
% Lys:
24
0
0
8
0
54
16
0
77
0
8
0
0
0
0
% K
% Leu:
8
47
8
0
0
0
0
0
8
0
0
0
0
0
8
% L
% Met:
0
8
0
0
0
0
8
0
0
0
0
0
8
0
8
% M
% Asn:
31
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% N
% Pro:
8
0
0
8
0
8
0
0
8
0
0
0
8
8
0
% P
% Gln:
0
0
0
0
0
8
0
0
0
8
0
0
8
0
0
% Q
% Arg:
0
0
8
0
0
24
0
8
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
8
0
0
62
0
0
0
62
70
8
0
% S
% Thr:
8
8
8
0
0
0
0
0
8
70
8
0
0
0
8
% T
% Val:
0
8
0
8
70
0
0
8
0
0
0
16
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _