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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIWIL1
All Species:
28.79
Human Site:
S123
Identified Species:
52.78
UniProt:
Q96J94
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96J94
NP_004755.2
861
98603
S123
T
N
H
F
R
L
T
S
R
P
Q
W
A
L
Y
Chimpanzee
Pan troglodytes
XP_001137815
861
98509
S123
T
N
H
F
R
L
T
S
R
P
Q
W
A
L
Y
Rhesus Macaque
Macaca mulatta
XP_001089264
852
96294
F117
T
N
L
F
N
L
D
F
P
Q
D
W
Q
L
Y
Dog
Lupus familis
XP_534638
861
98542
S123
T
N
H
F
R
L
T
S
R
P
Q
W
A
L
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q9JMB7
862
98556
S124
T
N
H
F
R
L
T
S
R
P
Q
W
A
L
Y
Rat
Rattus norvegicus
Q4G033
848
95953
L112
T
N
L
F
H
L
D
L
P
Q
D
W
Q
L
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509070
1180
134396
S442
T
N
H
F
R
L
T
S
R
P
Q
W
A
L
Y
Chicken
Gallus gallus
A6N7Y9
867
99268
S131
A
N
F
F
R
L
T
S
R
P
Q
W
A
L
Y
Frog
Xenopus laevis
Q6DCX2
862
97626
T121
K
Q
V
E
L
E
V
T
L
P
G
E
G
K
D
Zebra Danio
Brachydanio rerio
Q8UVX0
858
97433
S121
A
N
F
M
R
L
L
S
R
P
M
W
A
L
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VKM1
843
97159
E111
F
R
L
K
T
K
P
E
W
R
I
V
H
Y
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_999765
854
96704
T118
A
N
G
F
K
L
K
T
K
P
D
W
Q
L
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04379
1048
116172
E202
K
A
N
H
F
F
A
E
L
P
D
K
D
L
H
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
49.3
95.9
N.A.
94.9
50
N.A.
63.9
77
24.5
64.8
N.A.
35.7
N.A.
N.A.
47.6
Protein Similarity:
100
99.5
67.7
97.9
N.A.
97.4
68
N.A.
69.3
88.1
44.7
80.1
N.A.
57.2
N.A.
N.A.
64.3
P-Site Identity:
100
100
46.6
100
N.A.
100
46.6
N.A.
100
86.6
6.6
66.6
N.A.
0
N.A.
N.A.
46.6
P-Site Similarity:
100
100
46.6
100
N.A.
100
46.6
N.A.
100
86.6
13.3
66.6
N.A.
6.6
N.A.
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.8
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
24
8
0
0
0
0
8
0
0
0
0
0
54
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
16
0
0
0
31
0
8
0
8
% D
% Glu:
0
0
0
8
0
8
0
16
0
0
0
8
0
0
0
% E
% Phe:
8
0
16
70
8
8
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
0
0
0
0
0
0
8
0
8
0
0
% G
% His:
0
0
39
8
8
0
0
0
0
0
0
0
8
0
16
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% I
% Lys:
16
0
0
8
8
8
8
0
8
0
0
8
0
8
0
% K
% Leu:
0
0
24
0
8
77
8
8
16
0
0
0
0
85
0
% L
% Met:
0
0
0
8
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
77
8
0
8
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
8
0
16
77
0
0
0
0
0
% P
% Gln:
0
8
0
0
0
0
0
0
0
16
47
0
24
0
0
% Q
% Arg:
0
8
0
0
54
0
0
0
54
8
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
54
0
0
0
0
0
0
0
% S
% Thr:
54
0
0
0
8
0
47
16
0
0
0
0
0
0
0
% T
% Val:
0
0
8
0
0
0
8
0
0
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
77
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
77
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _