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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PIWIL1 All Species: 28.79
Human Site: S123 Identified Species: 52.78
UniProt: Q96J94 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96J94 NP_004755.2 861 98603 S123 T N H F R L T S R P Q W A L Y
Chimpanzee Pan troglodytes XP_001137815 861 98509 S123 T N H F R L T S R P Q W A L Y
Rhesus Macaque Macaca mulatta XP_001089264 852 96294 F117 T N L F N L D F P Q D W Q L Y
Dog Lupus familis XP_534638 861 98542 S123 T N H F R L T S R P Q W A L Y
Cat Felis silvestris
Mouse Mus musculus Q9JMB7 862 98556 S124 T N H F R L T S R P Q W A L Y
Rat Rattus norvegicus Q4G033 848 95953 L112 T N L F H L D L P Q D W Q L Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509070 1180 134396 S442 T N H F R L T S R P Q W A L Y
Chicken Gallus gallus A6N7Y9 867 99268 S131 A N F F R L T S R P Q W A L Y
Frog Xenopus laevis Q6DCX2 862 97626 T121 K Q V E L E V T L P G E G K D
Zebra Danio Brachydanio rerio Q8UVX0 858 97433 S121 A N F M R L L S R P M W A L Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VKM1 843 97159 E111 F R L K T K P E W R I V H Y H
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_999765 854 96704 T118 A N G F K L K T K P D W Q L Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O04379 1048 116172 E202 K A N H F F A E L P D K D L H
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 49.3 95.9 N.A. 94.9 50 N.A. 63.9 77 24.5 64.8 N.A. 35.7 N.A. N.A. 47.6
Protein Similarity: 100 99.5 67.7 97.9 N.A. 97.4 68 N.A. 69.3 88.1 44.7 80.1 N.A. 57.2 N.A. N.A. 64.3
P-Site Identity: 100 100 46.6 100 N.A. 100 46.6 N.A. 100 86.6 6.6 66.6 N.A. 0 N.A. N.A. 46.6
P-Site Similarity: 100 100 46.6 100 N.A. 100 46.6 N.A. 100 86.6 13.3 66.6 N.A. 6.6 N.A. N.A. 66.6
Percent
Protein Identity: N.A. N.A. N.A. 23.8 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 40.4 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 24 8 0 0 0 0 8 0 0 0 0 0 54 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 16 0 0 0 31 0 8 0 8 % D
% Glu: 0 0 0 8 0 8 0 16 0 0 0 8 0 0 0 % E
% Phe: 8 0 16 70 8 8 0 8 0 0 0 0 0 0 0 % F
% Gly: 0 0 8 0 0 0 0 0 0 0 8 0 8 0 0 % G
% His: 0 0 39 8 8 0 0 0 0 0 0 0 8 0 16 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % I
% Lys: 16 0 0 8 8 8 8 0 8 0 0 8 0 8 0 % K
% Leu: 0 0 24 0 8 77 8 8 16 0 0 0 0 85 0 % L
% Met: 0 0 0 8 0 0 0 0 0 0 8 0 0 0 0 % M
% Asn: 0 77 8 0 8 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 8 0 16 77 0 0 0 0 0 % P
% Gln: 0 8 0 0 0 0 0 0 0 16 47 0 24 0 0 % Q
% Arg: 0 8 0 0 54 0 0 0 54 8 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 54 0 0 0 0 0 0 0 % S
% Thr: 54 0 0 0 8 0 47 16 0 0 0 0 0 0 0 % T
% Val: 0 0 8 0 0 0 8 0 0 0 0 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 8 0 0 77 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 77 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _