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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIWIL1
All Species:
14.24
Human Site:
S27
Identified Species:
26.11
UniProt:
Q96J94
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96J94
NP_004755.2
861
98603
S27
Q
L
V
G
S
T
A
S
Q
Q
P
G
Y
I
Q
Chimpanzee
Pan troglodytes
XP_001137815
861
98509
S27
Q
L
V
G
S
T
A
S
Q
Q
P
G
Y
I
Q
Rhesus Macaque
Macaca mulatta
XP_001089264
852
96294
A27
E
V
G
R
T
Q
A
A
P
L
P
T
S
V
D
Dog
Lupus familis
XP_534638
861
98542
S27
Q
H
V
G
A
T
V
S
Q
Q
P
G
Y
V
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9JMB7
862
98556
S27
Q
H
V
G
A
A
A
S
Q
Q
P
G
Y
I
P
Rat
Rattus norvegicus
Q4G033
848
95953
R26
R
E
V
E
R
A
P
R
D
L
M
V
T
S
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509070
1180
134396
N111
Q
I
I
L
T
K
A
N
K
G
I
S
V
T
L
Chicken
Gallus gallus
A6N7Y9
867
99268
A28
P
P
V
G
A
A
S
A
Q
K
T
L
P
S
H
Frog
Xenopus laevis
Q6DCX2
862
97626
K26
P
M
P
A
Y
T
F
K
P
P
P
R
P
D
F
Zebra Danio
Brachydanio rerio
Q8UVX0
858
97433
V27
A
P
G
A
Q
P
P
V
S
Q
E
A
A
K
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VKM1
843
97159
D26
S
T
S
R
G
S
G
D
G
P
R
V
K
V
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_999765
854
96704
R31
S
G
M
P
V
P
G
R
G
R
S
R
G
G
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04379
1048
116172
S32
V
S
G
G
G
R
G
S
Q
R
G
G
F
Q
Q
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
49.3
95.9
N.A.
94.9
50
N.A.
63.9
77
24.5
64.8
N.A.
35.7
N.A.
N.A.
47.6
Protein Similarity:
100
99.5
67.7
97.9
N.A.
97.4
68
N.A.
69.3
88.1
44.7
80.1
N.A.
57.2
N.A.
N.A.
64.3
P-Site Identity:
100
100
13.3
73.3
N.A.
73.3
6.6
N.A.
13.3
20
13.3
6.6
N.A.
0
N.A.
N.A.
0
P-Site Similarity:
100
100
46.6
86.6
N.A.
80
13.3
N.A.
46.6
46.6
20
6.6
N.A.
13.3
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.8
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
16
24
24
39
16
0
0
0
8
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
8
8
0
0
0
0
8
8
% D
% Glu:
8
8
0
8
0
0
0
0
0
0
8
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
0
0
8
0
16
% F
% Gly:
0
8
24
47
16
0
24
0
16
8
8
39
8
8
0
% G
% His:
0
16
0
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
8
8
0
0
0
0
0
0
0
8
0
0
24
0
% I
% Lys:
0
0
0
0
0
8
0
8
8
8
0
0
8
8
0
% K
% Leu:
0
16
0
8
0
0
0
0
0
16
0
8
0
0
8
% L
% Met:
0
8
8
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
16
16
8
8
0
16
16
0
16
16
47
0
16
0
16
% P
% Gln:
39
0
0
0
8
8
0
0
47
39
0
0
0
8
31
% Q
% Arg:
8
0
0
16
8
8
0
16
0
16
8
16
0
0
0
% R
% Ser:
16
8
8
0
16
8
8
39
8
0
8
8
8
16
0
% S
% Thr:
0
8
0
0
16
31
0
0
0
0
8
8
8
8
8
% T
% Val:
8
8
47
0
8
0
8
8
0
0
0
16
8
24
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
0
0
0
31
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _