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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PIWIL1 All Species: 23.92
Human Site: S855 Identified Species: 43.85
UniProt: Q96J94 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96J94 NP_004755.2 861 98603 S855 R E P N L S L S N R L Y Y L _
Chimpanzee Pan troglodytes XP_001137815 861 98509 S855 R E P N L S L S N R L Y Y L _
Rhesus Macaque Macaca mulatta XP_001089264 852 96294 A846 K E P S L E L A N H L F Y L _
Dog Lupus familis XP_534638 861 98542 S855 R E P N L S L S N R L Y Y L _
Cat Felis silvestris
Mouse Mus musculus Q9JMB7 862 98556 S856 R E P N L S L S N R L Y Y L _
Rat Rattus norvegicus Q4G033 848 95953 A842 K E P S L E L A N K L F Y L _
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509070 1180 134396 T1174 R E P S L S L T D R L Y Y L _
Chicken Gallus gallus A6N7Y9 867 99268 S861 R E P N L L L S D R L Y Y L _
Frog Xenopus laevis Q6DCX2 862 97626 E829 D K E H D S A E G S H T S G Q
Zebra Danio Brachydanio rerio Q8UVX0 858 97433 D852 K E P N M N L D D F L Y Y L _
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VKM1 843 97159 E837 S I P Q N A L E K K F Y Y L _
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_999765 854 96704 A848 E V P N N R L A D T L F Y L _
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O04379 1048 116172 S1005 P E T S D S G S M A S G S M A
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 49.3 95.9 N.A. 94.9 50 N.A. 63.9 77 24.5 64.8 N.A. 35.7 N.A. N.A. 47.6
Protein Similarity: 100 99.5 67.7 97.9 N.A. 97.4 68 N.A. 69.3 88.1 44.7 80.1 N.A. 57.2 N.A. N.A. 64.3
P-Site Identity: 100 100 57.1 100 N.A. 100 57.1 N.A. 78.5 85.7 6.6 57.1 N.A. 35.7 N.A. N.A. 42.8
P-Site Similarity: 100 100 85.7 100 N.A. 100 92.8 N.A. 100 92.8 20 85.7 N.A. 50 N.A. N.A. 64.2
Percent
Protein Identity: N.A. N.A. N.A. 23.8 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 40.4 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 20 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 8 8 24 0 8 0 0 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 0 16 0 0 8 31 0 0 0 0 0 0 % D
% Glu: 8 77 8 0 0 16 0 16 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 8 8 24 0 0 0 % F
% Gly: 0 0 0 0 0 0 8 0 8 0 0 8 0 8 0 % G
% His: 0 0 0 8 0 0 0 0 0 8 8 0 0 0 0 % H
% Ile: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 24 8 0 0 0 0 0 0 8 16 0 0 0 0 0 % K
% Leu: 0 0 0 0 62 8 85 0 0 0 77 0 0 85 0 % L
% Met: 0 0 0 0 8 0 0 0 8 0 0 0 0 8 0 % M
% Asn: 0 0 0 54 16 8 0 0 47 0 0 0 0 0 0 % N
% Pro: 8 0 85 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 8 % Q
% Arg: 47 0 0 0 0 8 0 0 0 47 0 0 0 0 0 % R
% Ser: 8 0 0 31 0 54 0 47 0 8 8 0 16 0 0 % S
% Thr: 0 0 8 0 0 0 0 8 0 8 0 8 0 0 0 % T
% Val: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 62 85 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 85 % _