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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIWIL1
All Species:
14.55
Human Site:
T375
Identified Species:
26.67
UniProt:
Q96J94
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96J94
NP_004755.2
861
98603
T375
R
R
R
G
P
G
G
T
L
P
G
P
A
M
L
Chimpanzee
Pan troglodytes
XP_001137815
861
98509
T375
R
R
R
G
P
G
G
T
L
P
G
P
A
M
L
Rhesus Macaque
Macaca mulatta
XP_001089264
852
96294
E369
R
K
R
N
D
N
S
E
A
R
L
A
H
L
I
Dog
Lupus familis
XP_534638
861
98542
T375
R
R
R
G
P
G
G
T
L
P
G
P
A
M
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9JMB7
862
98556
T376
R
R
R
G
P
G
G
T
L
P
G
P
A
M
L
Rat
Rattus norvegicus
Q4G033
848
95953
E364
R
R
R
N
D
N
S
E
P
Q
M
V
H
L
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509070
1180
134396
A694
R
R
R
G
P
G
G
A
L
P
G
P
A
L
L
Chicken
Gallus gallus
A6N7Y9
867
99268
V383
R
K
R
G
N
V
T
V
G
P
V
V
L
I
P
Frog
Xenopus laevis
Q6DCX2
862
97626
S365
K
L
T
D
N
Q
T
S
T
M
I
R
A
T
A
Zebra Danio
Brachydanio rerio
Q8UVX0
858
97433
P373
L
G
P
S
G
R
P
P
P
G
P
A
M
L
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VKM1
843
97159
L360
L
K
T
N
A
S
E
L
V
V
L
I
P
E
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_999765
854
96704
P370
E
E
K
K
G
V
G
P
A
Y
L
P
P
E
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04379
1048
116172
N485
L
P
C
L
Q
V
G
N
S
N
R
P
N
Y
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
49.3
95.9
N.A.
94.9
50
N.A.
63.9
77
24.5
64.8
N.A.
35.7
N.A.
N.A.
47.6
Protein Similarity:
100
99.5
67.7
97.9
N.A.
97.4
68
N.A.
69.3
88.1
44.7
80.1
N.A.
57.2
N.A.
N.A.
64.3
P-Site Identity:
100
100
13.3
100
N.A.
100
20
N.A.
86.6
26.6
6.6
0
N.A.
6.6
N.A.
N.A.
20
P-Site Similarity:
100
100
33.3
100
N.A.
100
33.3
N.A.
93.3
40
20
13.3
N.A.
20
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.8
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
8
16
0
0
16
47
0
8
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
16
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
8
8
0
0
0
0
8
16
0
0
0
0
0
16
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
47
16
39
54
0
8
8
39
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
16
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
8
8
0
8
16
% I
% Lys:
8
24
8
8
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
24
8
0
8
0
0
0
8
39
0
24
0
8
31
62
% L
% Met:
0
0
0
0
0
0
0
0
0
8
8
0
8
31
0
% M
% Asn:
0
0
0
24
16
16
0
8
0
8
0
0
8
0
0
% N
% Pro:
0
8
8
0
39
0
8
16
16
47
8
54
16
0
8
% P
% Gln:
0
0
0
0
8
8
0
0
0
8
0
0
0
0
0
% Q
% Arg:
62
47
62
0
0
8
0
0
0
8
8
8
0
0
0
% R
% Ser:
0
0
0
8
0
8
16
8
8
0
0
0
0
0
0
% S
% Thr:
0
0
16
0
0
0
16
31
8
0
0
0
0
8
0
% T
% Val:
0
0
0
0
0
24
0
8
8
8
8
16
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _