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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIWIL1
All Species:
38.48
Human Site:
Y233
Identified Species:
70.56
UniProt:
Q96J94
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96J94
NP_004755.2
861
98603
Y233
Q
Q
I
G
R
N
Y
Y
N
P
N
D
P
I
D
Chimpanzee
Pan troglodytes
XP_001137815
861
98509
Y233
Q
Q
I
G
R
N
Y
Y
N
P
N
D
P
I
D
Rhesus Macaque
Macaca mulatta
XP_001089264
852
96294
Y227
Y
Q
I
G
R
N
F
Y
N
P
S
E
P
V
E
Dog
Lupus familis
XP_534638
861
98542
Y233
Q
Q
I
G
R
N
Y
Y
N
P
S
D
P
I
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9JMB7
862
98556
Y234
Q
Q
I
G
R
N
Y
Y
N
P
S
D
P
I
D
Rat
Rattus norvegicus
Q4G033
848
95953
Y222
Y
Q
I
G
R
N
Y
Y
K
P
S
E
P
V
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509070
1180
134396
Y552
Q
Q
I
G
R
N
Y
Y
N
P
S
D
P
I
S
Chicken
Gallus gallus
A6N7Y9
867
99268
Y241
Q
Q
I
G
R
N
Y
Y
N
P
K
D
P
V
S
Frog
Xenopus laevis
Q6DCX2
862
97626
S223
M
M
L
N
I
D
V
S
A
T
A
F
Y
K
A
Zebra Danio
Brachydanio rerio
Q8UVX0
858
97433
Y231
Q
Q
I
G
R
H
Y
Y
N
P
D
D
P
F
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VKM1
843
97159
F218
E
L
V
G
R
N
L
F
D
P
R
A
K
I
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_999765
854
96704
Y228
E
Q
V
G
R
N
Y
Y
D
P
T
A
A
I
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04379
1048
116172
P343
V
G
R
S
F
Y
S
P
D
I
G
K
K
Q
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
49.3
95.9
N.A.
94.9
50
N.A.
63.9
77
24.5
64.8
N.A.
35.7
N.A.
N.A.
47.6
Protein Similarity:
100
99.5
67.7
97.9
N.A.
97.4
68
N.A.
69.3
88.1
44.7
80.1
N.A.
57.2
N.A.
N.A.
64.3
P-Site Identity:
100
100
60
93.3
N.A.
93.3
60
N.A.
86.6
80
0
73.3
N.A.
33.3
N.A.
N.A.
60
P-Site Similarity:
100
100
93.3
100
N.A.
100
86.6
N.A.
93.3
86.6
13.3
93.3
N.A.
66.6
N.A.
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.8
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
8
0
8
16
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
0
0
24
0
8
54
0
0
39
% D
% Glu:
16
0
0
0
0
0
0
0
0
0
0
16
0
0
24
% E
% Phe:
0
0
0
0
8
0
8
8
0
0
0
8
0
8
0
% F
% Gly:
0
8
0
85
0
0
0
0
0
0
8
0
0
0
0
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
70
0
8
0
0
0
0
8
0
0
0
54
0
% I
% Lys:
0
0
0
0
0
0
0
0
8
0
8
8
16
8
0
% K
% Leu:
0
8
8
0
0
0
8
0
0
0
0
0
0
0
0
% L
% Met:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
77
0
0
62
0
16
0
0
0
8
% N
% Pro:
0
0
0
0
0
0
0
8
0
85
0
0
70
0
0
% P
% Gln:
54
77
0
0
0
0
0
0
0
0
0
0
0
8
0
% Q
% Arg:
0
0
8
0
85
0
0
0
0
0
8
0
0
0
0
% R
% Ser:
0
0
0
8
0
0
8
8
0
0
39
0
0
0
24
% S
% Thr:
0
0
0
0
0
0
0
0
0
8
8
0
0
0
0
% T
% Val:
8
0
16
0
0
0
8
0
0
0
0
0
0
24
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
16
0
0
0
0
8
70
77
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _