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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIWIL1
All Species:
21.82
Human Site:
Y427
Identified Species:
40
UniProt:
Q96J94
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96J94
NP_004755.2
861
98603
Y427
E
V
G
R
L
I
D
Y
I
H
K
N
D
N
V
Chimpanzee
Pan troglodytes
XP_001137815
861
98509
Y427
E
V
G
R
L
I
D
Y
I
H
K
N
D
N
V
Rhesus Macaque
Macaca mulatta
XP_001089264
852
96294
N420
R
L
A
R
L
V
D
N
I
Q
R
N
T
N
A
Dog
Lupus familis
XP_534638
861
98542
Y427
E
V
G
R
L
I
D
Y
I
H
K
D
D
N
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9JMB7
862
98556
Y428
E
V
G
R
L
I
D
Y
I
H
K
D
D
N
V
Rat
Rattus norvegicus
Q4G033
848
95953
D415
Q
L
A
R
L
A
D
D
I
Q
R
N
Q
V
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509070
1180
134396
Y746
E
V
G
R
L
I
D
Y
I
H
K
D
D
N
V
Chicken
Gallus gallus
A6N7Y9
867
99268
C433
E
I
G
K
L
V
D
C
M
K
K
D
E
C
V
Frog
Xenopus laevis
Q6DCX2
862
97626
Y423
L
Q
P
P
S
I
L
Y
G
G
R
S
K
A
I
Zebra Danio
Brachydanio rerio
Q8UVX0
858
97433
N424
R
I
N
R
L
I
S
N
I
N
R
N
G
D
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VKM1
843
97159
N411
A
F
N
H
R
L
Q
N
T
P
E
S
V
K
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_999765
854
96704
S420
S
G
F
I
K
K
L
S
S
N
E
E
V
K
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04379
1048
116172
T535
R
E
K
D
I
L
Q
T
V
Q
L
N
D
Y
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
49.3
95.9
N.A.
94.9
50
N.A.
63.9
77
24.5
64.8
N.A.
35.7
N.A.
N.A.
47.6
Protein Similarity:
100
99.5
67.7
97.9
N.A.
97.4
68
N.A.
69.3
88.1
44.7
80.1
N.A.
57.2
N.A.
N.A.
64.3
P-Site Identity:
100
100
40
93.3
N.A.
93.3
33.3
N.A.
93.3
40
13.3
40
N.A.
6.6
N.A.
N.A.
0
P-Site Similarity:
100
100
60
100
N.A.
100
53.3
N.A.
100
80
33.3
66.6
N.A.
26.6
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.8
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
16
0
0
8
0
0
0
0
0
0
0
8
16
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
8
0
% C
% Asp:
0
0
0
8
0
0
62
8
0
0
0
31
47
8
0
% D
% Glu:
47
8
0
0
0
0
0
0
0
0
16
8
8
0
0
% E
% Phe:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
47
0
0
0
0
0
8
8
0
0
8
0
0
% G
% His:
0
0
0
8
0
0
0
0
0
39
0
0
0
0
0
% H
% Ile:
0
16
0
8
8
54
0
0
62
0
0
0
0
0
8
% I
% Lys:
0
0
8
8
8
8
0
0
0
8
47
0
8
16
0
% K
% Leu:
8
16
0
0
70
16
16
0
0
0
8
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
16
0
0
0
0
24
0
16
0
47
0
47
0
% N
% Pro:
0
0
8
8
0
0
0
0
0
8
0
0
0
0
0
% P
% Gln:
8
8
0
0
0
0
16
0
0
24
0
0
8
0
0
% Q
% Arg:
24
0
0
62
8
0
0
0
0
0
31
0
0
0
0
% R
% Ser:
8
0
0
0
8
0
8
8
8
0
0
16
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
8
8
0
0
0
8
0
16
% T
% Val:
0
39
0
0
0
16
0
0
8
0
0
0
16
8
62
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
47
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _