KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIWIL1
All Species:
27.58
Human Site:
Y541
Identified Species:
50.56
UniProt:
Q96J94
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96J94
NP_004755.2
861
98603
Y541
V
D
D
R
T
E
A
Y
L
R
V
L
Q
Q
K
Chimpanzee
Pan troglodytes
XP_001137815
861
98509
Y541
V
D
D
R
T
E
A
Y
L
R
V
L
Q
Q
K
Rhesus Macaque
Macaca mulatta
XP_001089264
852
96294
F532
V
Q
E
N
P
A
A
F
V
R
A
V
Q
Q
Y
Dog
Lupus familis
XP_534638
861
98542
Y541
V
D
D
R
T
E
A
Y
L
R
V
L
Q
Q
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9JMB7
862
98556
Y542
V
D
D
R
T
E
A
Y
L
R
A
L
Q
Q
K
Rat
Rattus norvegicus
Q4G033
848
95953
F527
V
D
E
N
P
A
A
F
L
R
A
I
Q
L
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509070
1180
134396
Y860
V
D
D
R
T
E
A
Y
L
R
V
L
Q
Q
K
Chicken
Gallus gallus
A6N7Y9
867
99268
Y547
V
D
D
R
T
E
A
Y
L
R
V
L
Q
Q
S
Frog
Xenopus laevis
Q6DCX2
862
97626
G544
R
V
G
D
T
V
L
G
M
A
T
Q
C
V
Q
Zebra Danio
Brachydanio rerio
Q8UVX0
858
97433
L538
Y
E
D
R
Q
E
S
L
L
R
A
L
Q
Q
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VKM1
843
97159
Y524
Y
D
D
R
T
G
T
Y
V
R
A
M
D
D
C
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_999765
854
96704
Y533
P
D
D
R
T
E
T
Y
T
R
S
L
Q
A
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04379
1048
116172
H662
K
V
L
K
T
R
Y
H
D
A
T
S
K
L
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
49.3
95.9
N.A.
94.9
50
N.A.
63.9
77
24.5
64.8
N.A.
35.7
N.A.
N.A.
47.6
Protein Similarity:
100
99.5
67.7
97.9
N.A.
97.4
68
N.A.
69.3
88.1
44.7
80.1
N.A.
57.2
N.A.
N.A.
64.3
P-Site Identity:
100
100
33.3
100
N.A.
93.3
40
N.A.
100
93.3
6.6
53.3
N.A.
40
N.A.
N.A.
60
P-Site Similarity:
100
100
60
100
N.A.
93.3
60
N.A.
100
93.3
20
66.6
N.A.
53.3
N.A.
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.8
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
16
62
0
0
16
39
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% C
% Asp:
0
70
70
8
0
0
0
0
8
0
0
0
8
8
0
% D
% Glu:
0
8
16
0
0
62
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
16
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
0
8
0
8
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
8
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% I
% Lys:
8
0
0
8
0
0
0
0
0
0
0
0
8
0
39
% K
% Leu:
0
0
8
0
0
0
8
8
62
0
0
62
0
16
0
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
8
0
0
0
% M
% Asn:
0
0
0
16
0
0
0
0
0
0
0
0
0
0
8
% N
% Pro:
8
0
0
0
16
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
0
8
0
0
0
0
0
0
8
77
62
16
% Q
% Arg:
8
0
0
70
0
8
0
0
0
85
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
8
0
0
0
8
8
0
0
16
% S
% Thr:
0
0
0
0
77
0
16
0
8
0
16
0
0
0
0
% T
% Val:
62
16
0
0
0
8
0
0
16
0
39
8
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
16
0
0
0
0
0
8
62
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _