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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIWIL1
All Species:
41.82
Human Site:
Y568
Identified Species:
76.67
UniProt:
Q96J94
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96J94
NP_004755.2
861
98603
Y568
S
S
N
R
K
D
K
Y
D
A
I
K
K
Y
L
Chimpanzee
Pan troglodytes
XP_001137815
861
98509
Y568
S
S
N
R
K
D
K
Y
D
A
I
K
K
Y
L
Rhesus Macaque
Macaca mulatta
XP_001089264
852
96294
Y559
P
S
N
Q
K
T
Y
Y
D
S
I
K
K
Y
L
Dog
Lupus familis
XP_534638
861
98542
Y568
S
S
N
R
K
D
K
Y
D
A
I
K
K
Y
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9JMB7
862
98556
Y569
S
S
N
R
K
D
K
Y
D
A
I
K
K
Y
L
Rat
Rattus norvegicus
Q4G033
848
95953
Y554
P
S
N
Q
K
N
Y
Y
D
S
I
K
R
Y
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509070
1180
134396
Y887
S
S
N
R
K
D
K
Y
D
A
I
K
K
Y
L
Chicken
Gallus gallus
A6N7Y9
867
99268
Y574
S
S
T
R
K
D
K
Y
D
A
I
K
K
Y
L
Frog
Xenopus laevis
Q6DCX2
862
97626
N571
S
N
L
C
L
K
I
N
V
K
L
G
G
V
N
Zebra Danio
Brachydanio rerio
Q8UVX0
858
97433
Y565
P
T
N
R
K
D
K
Y
D
C
V
K
K
Y
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VKM1
843
97159
Y551
P
N
D
N
A
E
R
Y
S
S
I
K
K
R
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_999765
854
96704
Y560
P
T
N
R
K
D
R
Y
D
A
I
K
K
T
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04379
1048
116172
Y689
P
D
N
N
G
S
L
Y
G
D
L
K
R
I
C
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
49.3
95.9
N.A.
94.9
50
N.A.
63.9
77
24.5
64.8
N.A.
35.7
N.A.
N.A.
47.6
Protein Similarity:
100
99.5
67.7
97.9
N.A.
97.4
68
N.A.
69.3
88.1
44.7
80.1
N.A.
57.2
N.A.
N.A.
64.3
P-Site Identity:
100
100
66.6
100
N.A.
100
60
N.A.
100
93.3
6.6
73.3
N.A.
26.6
N.A.
N.A.
66.6
P-Site Similarity:
100
100
80
100
N.A.
100
86.6
N.A.
100
93.3
20
86.6
N.A.
60
N.A.
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.8
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
0
0
54
0
0
0
0
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
8
0
0
0
0
16
% C
% Asp:
0
8
8
0
0
62
0
0
77
8
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
8
0
0
0
8
0
0
8
8
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
8
0
0
0
77
0
0
8
0
% I
% Lys:
0
0
0
0
77
8
54
0
0
8
0
93
77
0
0
% K
% Leu:
0
0
8
0
8
0
8
0
0
0
16
0
0
0
70
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
16
77
16
0
8
0
8
0
0
0
0
0
0
8
% N
% Pro:
47
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
16
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
62
0
0
16
0
0
0
0
0
16
8
0
% R
% Ser:
54
62
0
0
0
8
0
0
8
24
0
0
0
0
0
% S
% Thr:
0
16
8
0
0
8
0
0
0
0
0
0
0
8
0
% T
% Val:
0
0
0
0
0
0
0
0
8
0
8
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
16
93
0
0
0
0
0
70
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _