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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLEKHA8
All Species:
21.21
Human Site:
T381
Identified Species:
66.67
UniProt:
Q96JA3
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96JA3
NP_116028.1
519
58306
T381
T
N
K
E
E
F
T
T
L
Q
K
I
V
L
H
Chimpanzee
Pan troglodytes
XP_527709
519
58225
T381
T
N
K
E
E
F
T
T
L
Q
K
I
V
L
H
Rhesus Macaque
Macaca mulatta
XP_001086395
519
58066
T381
T
N
K
E
E
F
T
T
L
Q
K
I
V
L
H
Dog
Lupus familis
XP_545547
293
32986
K168
T
T
L
E
E
C
V
K
I
A
N
A
K
F
K
Cat
Felis silvestris
Mouse
Mus musculus
Q80W71
519
57943
T381
T
N
K
E
E
F
T
T
L
Q
K
I
V
L
H
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418736
519
58539
T381
T
N
K
E
E
F
D
T
L
Q
K
I
V
L
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5U3N0
549
61436
T411
S
D
P
E
S
F
P
T
L
Q
S
I
V
L
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001197978
511
56706
M370
M
F
M
K
L
Q
A
M
V
Q
Q
E
V
R
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
98
29
N.A.
92
N.A.
N.A.
N.A.
73.5
N.A.
58.6
N.A.
N.A.
N.A.
N.A.
38.1
Protein Similarity:
100
99.6
99
41.4
N.A.
96.3
N.A.
N.A.
N.A.
83.4
N.A.
71.4
N.A.
N.A.
N.A.
N.A.
55.6
P-Site Identity:
100
100
100
20
N.A.
100
N.A.
N.A.
N.A.
93.3
N.A.
60
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
26.6
N.A.
100
N.A.
N.A.
N.A.
93.3
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
13
0
0
13
0
13
0
0
0
% A
% Cys:
0
0
0
0
0
13
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
13
0
0
0
0
13
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
88
75
0
0
0
0
0
0
13
0
0
0
% E
% Phe:
0
13
0
0
0
75
0
0
0
0
0
0
0
13
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
75
% H
% Ile:
0
0
0
0
0
0
0
0
13
0
0
75
0
0
0
% I
% Lys:
0
0
63
13
0
0
0
13
0
0
63
0
13
0
13
% K
% Leu:
0
0
13
0
13
0
0
0
75
0
0
0
0
75
0
% L
% Met:
13
0
13
0
0
0
0
13
0
0
0
0
0
0
0
% M
% Asn:
0
63
0
0
0
0
0
0
0
0
13
0
0
0
0
% N
% Pro:
0
0
13
0
0
0
13
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
13
0
0
0
88
13
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
0
% R
% Ser:
13
0
0
0
13
0
0
0
0
0
13
0
0
0
0
% S
% Thr:
75
13
0
0
0
0
50
75
0
0
0
0
0
0
13
% T
% Val:
0
0
0
0
0
0
13
0
13
0
0
0
88
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _