KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COG3
All Species:
20.91
Human Site:
S514
Identified Species:
38.33
UniProt:
Q96JB2
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96JB2
NP_113619.1
828
94096
S514
K
K
V
P
S
E
A
S
F
S
D
V
H
L
E
Chimpanzee
Pan troglodytes
XP_001158886
790
89707
A487
K
P
A
P
G
D
L
A
Y
P
D
K
L
V
M
Rhesus Macaque
Macaca mulatta
XP_001096875
828
94056
S514
K
K
V
P
S
E
A
S
F
S
D
V
H
L
E
Dog
Lupus familis
XP_848489
830
94828
S516
K
K
V
P
S
E
A
S
F
S
D
V
R
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8CI04
820
93264
S506
K
K
A
P
S
E
A
S
F
S
D
V
R
L
E
Rat
Rattus norvegicus
NP_001012157
828
94228
S514
K
K
T
P
S
E
A
S
F
S
D
V
R
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417041
835
94848
S511
K
K
L
P
S
E
A
S
F
S
D
V
R
L
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001137512
820
93798
K507
S
L
K
E
E
Q
M
K
L
N
S
S
N
S
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q961G1
905
101221
R502
L
Q
E
P
A
P
L
R
R
S
D
S
R
N
S
Honey Bee
Apis mellifera
XP_393867
799
92557
I480
R
Q
T
K
M
K
K
I
S
I
S
S
N
D
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001196648
781
87158
G486
S
G
S
A
L
M
S
G
Q
T
T
P
P
E
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_177485
784
88591
D476
N
Y
T
P
S
D
E
D
L
D
Y
P
A
K
L
Baker's Yeast
Sacchar. cerevisiae
P40094
801
92526
L491
D
D
N
P
D
P
L
L
E
S
Y
L
S
S
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.2
98.9
95
N.A.
94.9
96.2
N.A.
N.A.
86.4
N.A.
77
N.A.
40.2
41.5
N.A.
47.5
Protein Similarity:
100
95.4
99.7
97.1
N.A.
96.9
98.1
N.A.
N.A.
92.5
N.A.
87
N.A.
56.4
60.5
N.A.
63.1
P-Site Identity:
100
20
100
93.3
N.A.
86.6
86.6
N.A.
N.A.
86.6
N.A.
0
N.A.
20
0
N.A.
0
P-Site Similarity:
100
46.6
100
93.3
N.A.
86.6
86.6
N.A.
N.A.
93.3
N.A.
20
N.A.
33.3
33.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
35.7
21.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.8
43
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
16
8
8
0
47
8
0
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
0
0
8
16
0
8
0
8
62
0
0
8
8
% D
% Glu:
0
0
8
8
8
47
8
0
8
0
0
0
0
8
47
% E
% Phe:
0
0
0
0
0
0
0
0
47
0
0
0
0
0
16
% F
% Gly:
0
8
0
0
8
0
0
8
0
0
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
16
0
0
% H
% Ile:
0
0
0
0
0
0
0
8
0
8
0
0
0
0
0
% I
% Lys:
54
47
8
8
0
8
8
8
0
0
0
8
0
8
0
% K
% Leu:
8
8
8
0
8
0
24
8
16
0
0
8
8
47
8
% L
% Met:
0
0
0
0
8
8
8
0
0
0
0
0
0
0
8
% M
% Asn:
8
0
8
0
0
0
0
0
0
8
0
0
16
8
0
% N
% Pro:
0
8
0
77
0
16
0
0
0
8
0
16
8
0
0
% P
% Gln:
0
16
0
0
0
8
0
0
8
0
0
0
0
0
0
% Q
% Arg:
8
0
0
0
0
0
0
8
8
0
0
0
39
0
0
% R
% Ser:
16
0
8
0
54
0
8
47
8
62
16
24
8
16
8
% S
% Thr:
0
0
24
0
0
0
0
0
0
8
8
0
0
0
0
% T
% Val:
0
0
24
0
0
0
0
0
0
0
0
47
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
8
0
16
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _